LMPD Database

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LMP001586

UniProt Annotations

Entry Information
Gene NameUDP-glucose ceramide glucosyltransferase
Protein EntryO88693_MOUSE
UniProt IDO88693
SpeciesMouse
Comments
Comment typeDescription
Catalytic ActivityUDP-glucose + N-acylsphingosine = UDP + D- glucosyl-N-acylsphingosine.
FunctionCatalyzes the first glycosylation step in glycosphingolipid biosynthesis, the transfer of glucose to ceramide. May also serve as a "flippase" (By similarity).
PathwayLipid metabolism; sphingolipid metabolism.
SimilarityBelongs to the glycosyltransferase 2 family.
Subcellular LocationGolgi apparatus membrane ; Multi-pass membrane protein .