LMPD Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
LMP001584

UniProt Annotations

Entry Information
Gene Namemonoacylglycerol O-acyltransferase 1
Protein EntryMOGT1_MOUSE
UniProt IDQ91ZV4
SpeciesMouse
Comments
Comment typeDescription
Catalytic ActivityAcyl-CoA + 2-acylglycerol = CoA + diacylglycerol. {ECO:0000269|PubMed:12077311}.
FunctionCatalyzes the formation of diacylglycerol from 2- monoacylglycerol and fatty acyl-CoA. Probably not involved in absorption of dietary fat in the small intestine. {ECO:0000269|PubMed:12077311}.
PathwayGlycerolipid metabolism; triacylglycerol biosynthesis.
SimilarityBelongs to the diacylglycerol acyltransferase family. {ECO:0000305}.
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000305|PubMed:12077311}; Multi-pass membrane protein {ECO:0000305|PubMed:12077311}.
Tissue SpecificityExpressed at high level in kidney and stomach. Expressed at lower level in brown and white adipose tissue, uterus and liver. Not detected in small intestine. {ECO:0000269|PubMed:12077311}.