LMPD Database

LMP001563

Gene Information

Entrez Gene ID	27273
Gene Name	pyruvate dehydrogenase kinase, isoenzyme 4
Gene Symbol	Pdk4
Species	Mus musculus

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005743	IDA:MGI	C	mitochondrial inner membrane
GO:0005739	IDA:MGI	C	mitochondrion
GO:0005524	IEA:UniProtKB-KW	F	ATP binding
GO:0004674	IEA:UniProtKB-KW	F	protein serine/threonine kinase activity
GO:0004712	TAS:MGI	F	protein serine/threonine/tyrosine kinase activity
GO:0004740	ISS:UniProtKB	F	pyruvate dehydrogenase (acetyl-transferring) kinase activity
GO:0006086	TAS:MGI	P	acetyl-CoA biosynthetic process from pyruvate
GO:0071398	ISS:UniProtKB	P	cellular response to fatty acid
GO:0009267	ISS:UniProtKB	P	cellular response to starvation
GO:0042593	IMP:UniProtKB	P	glucose homeostasis
GO:0006006	IEA:UniProtKB-KW	P	glucose metabolic process
GO:0008286	IMP:UniProtKB	P	insulin receptor signaling pathway
GO:2000811	IEA:Ensembl	P	negative regulation of anoikis
GO:0006468	ISS:GOC	P	protein phosphorylation
GO:0072593	ISS:UniProtKB	P	reactive oxygen species metabolic process
GO:0010510	IMP:UniProtKB	P	regulation of acetyl-CoA biosynthetic process from pyruvate
GO:0045124	IMP:UniProtKB	P	regulation of bone resorption
GO:0010565	IMP:UniProtKB	P	regulation of cellular ketone metabolic process
GO:0042304	IMP:UniProtKB	P	regulation of fatty acid biosynthetic process
GO:0046320	IMP:UniProtKB	P	regulation of fatty acid oxidation
GO:0010906	IMP:UniProtKB	P	regulation of glucose metabolic process
GO:0006885	IMP:UniProtKB	P	regulation of pH
GO:0042594	IMP:UniProtKB	P	response to starvation

REACTOME Pathway Links

REACTOME Pathway ID	Description
5892778	Pyruvate metabolism
5893557	Regulation of pyruvate dehydrogenase (PDH) complex