LMPD Database

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LMP001419

Gene Information

Entrez Gene ID18762
Gene Nameprotein kinase C, zeta
Gene SymbolPrkcz
SpeciesMus musculus
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0045179 IDA:MGICapical cortex
GO:0016324 IDA:MGICapical plasma membrane
GO:0043203 IDA:MGICaxon hillock
GO:0005911 ISS:UniProtKBCcell-cell junction
GO:0005938 IDA:MGICcell cortex
GO:0031252 IEA:EnsemblCcell leading edge
GO:0005737 IDA:MGICcytoplasm
GO:0005829 IEA:EnsemblCcytosol
GO:0005768 IEA:UniProtKB-KWCendosome
GO:0070062 IEA:EnsemblCextracellular vesicular exosome
GO:0045121 IEA:EnsemblCmembrane raft
GO:0005815 IGI:MGICmicrotubule organizing center
GO:0035748 IDA:BHF-UCLCmyelin sheath abaxonal region
GO:0005635 IDA:MGICnuclear envelope
GO:0016363 IDA:MGICnuclear matrix
GO:0005634 IDA:MGICnucleus
GO:0048471 IEA:EnsemblCperinuclear region of cytoplasm
GO:0005886 IDA:MGICplasma membrane
GO:0043234 IDA:MGICprotein complex
GO:0005923 IDA:MGICtight junction
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0015459 IEA:EnsemblFpotassium channel regulator activity
GO:0004672 IDA:MGIFprotein kinase activity
GO:0004697 IEA:UniProtKB-ECFprotein kinase C activity
GO:0004674 IDA:UniProtKBFprotein serine/threonine kinase activity
GO:0008270 IEA:InterProFzinc ion binding
GO:0031532 IEA:EnsemblPactin cytoskeleton reorganization
GO:0031584 IEA:EnsemblPactivation of phospholipase D activity
GO:0032148 IEA:EnsemblPactivation of protein kinase B activity
GO:0016477 IEA:EnsemblPcell migration
GO:0030010 ISS:UniProtKBPestablishment of cell polarity
GO:0006954 IEA:UniProtKB-KWPinflammatory response
GO:0008286 IEA:EnsemblPinsulin receptor signaling pathway
GO:0007616 IEA:EnsemblPlong-term memory
GO:0060291 ISS:UniProtKBPlong-term synaptic potentiation
GO:0060081 IEA:EnsemblPmembrane hyperpolarization
GO:0000226 IMP:MGIPmicrotubule cytoskeleton organization
GO:0043066 IEA:EnsemblPnegative regulation of apoptotic process
GO:0051346 IEA:EnsemblPnegative regulation of hydrolase activity
GO:0046627 IEA:EnsemblPnegative regulation of insulin receptor signaling pathway
GO:0050732 IEA:EnsemblPnegative regulation of peptidyl-tyrosine phosphorylation
GO:0031333 IEA:EnsemblPnegative regulation of protein complex assembly
GO:1990138 IGI:MGIPneuron projection extension
GO:0018105 IEA:EnsemblPpeptidyl-serine phosphorylation
GO:0001954 IEA:EnsemblPpositive regulation of cell-matrix adhesion
GO:0008284 IEA:EnsemblPpositive regulation of cell proliferation
GO:0070374 ISS:UniProtKBPpositive regulation of ERK1 and ERK2 cascade
GO:2000463 ISS:UniProtKBPpositive regulation of excitatory postsynaptic membrane potential
GO:0046326 IEA:EnsemblPpositive regulation of glucose import
GO:0046628 ISS:UniProtKBPpositive regulation of insulin receptor signaling pathway
GO:2001181 IMP:UniProtKBPpositive regulation of interleukin-10 secretion
GO:2000667 IMP:UniProtKBPpositive regulation of interleukin-13 secretion
GO:0032753 IMP:UniProtKBPpositive regulation of interleukin-4 production
GO:2000664 IMP:UniProtKBPpositive regulation of interleukin-5 secretion
GO:0051092 ISS:UniProtKBPpositive regulation of NF-kappaB transcription factor activity
GO:2000553 IMP:UniProtKBPpositive regulation of T-helper 2 cell cytokine production
GO:0045630 IMP:UniProtKBPpositive regulation of T-helper 2 cell differentiation
GO:0051291 IEA:EnsemblPprotein heterooligomerization
GO:0070528 IEA:EnsemblPprotein kinase C signaling
GO:0072659 IMP:MGIPprotein localization to plasma membrane
GO:0006468 IDA:MGIPprotein phosphorylation
GO:0047496 IEA:EnsemblPvesicle transport along microtubule
KEGG Pathway Links
KEGG Pathway IDDescription
mmu04390Hippo signaling pathway
mmu04151PI3K-Akt signaling pathway
mmu04611Platelet activation
mmu04015Rap1 signaling pathway