LMPD Database

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LMP001384

Gene Information

Entrez Gene ID17969
Gene Nameneutrophil cytosolic factor 1
Gene SymbolNcf1
SpeciesMus musculus
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:MGICcytoplasm
GO:0005829 ISA:MGICcytosol
GO:0019898 ISS:UniProtKBCextrinsic component of membrane
GO:0043020 ISS:UniProtKBCNADPH oxidase complex
GO:0043325 ISS:UniProtKBFphosphatidylinositol-3,4-bisphosphate binding
GO:0035091 IEA:InterProFphosphatidylinositol binding
GO:0035091 ISS:UniProtKBFphosphatidylinositol binding
GO:0016175 IDA:MGIFsuperoxide-generating NADPH oxidase activity
GO:0008283 IMP:MGIPcell proliferation
GO:0006968 IMP:MGIPcellular defense response
GO:0042742 IMP:MGIPdefense response to bacterium
GO:0050832 IMP:MGIPdefense response to fungus
GO:0050830 IMP:MGIPdefense response to Gram-positive bacterium
GO:0050665 IMP:MGIPhydrogen peroxide biosynthetic process
GO:0006954 IMP:MGIPinflammatory response
GO:0001909 IMP:MGIPleukocyte mediated cytotoxicity
GO:0006691 IMP:MGIPleukotriene metabolic process
GO:0006742 ISA:MGIPNADP catabolic process
GO:0045986 IMP:MGIPnegative regulation of smooth muscle contraction
GO:0070947 IMP:MGIPneutrophil mediated killing of fungus
GO:0070946 IMP:MGIPneutrophil mediated killing of gram-positive bacterium
GO:0055114 IDA:GOCPoxidation-reduction process
GO:0006612 ISS:UniProtKBPprotein targeting to membrane
GO:0045730 IMP:MGIPrespiratory burst
GO:0002679 IMP:MGIPrespiratory burst involved in defense response
GO:0009617 IMP:MGIPresponse to bacterium
GO:0001878 IMP:MGIPresponse to yeast
GO:0042554 IMP:MGIPsuperoxide anion generation
KEGG Pathway Links
KEGG Pathway IDDescription
ko04062Chemokine signaling pathway
mmu04062Chemokine signaling pathway
ko04666Fc gamma R-mediated phagocytosis
mmu04666Fc gamma R-mediated phagocytosis
ko05140Leishmaniasis
mmu05140Leishmaniasis
ko04670Leukocyte transendothelial migration
mmu04670Leukocyte transendothelial migration
ko04380Osteoclast differentiation
mmu04380Osteoclast differentiation
ko04145Phagosome
mmu04145Phagosome
REACTOME Pathway Links
REACTOME Pathway IDDescription
5892925Adaptive Immune System
5893931Antigen processing-Cross presentation
5893914Class I MHC mediated antigen processing & presentation
5893934Cross-presentation of particulate exogenous antigens (phagosomes)
5892763Disease
5892920Immune System
5893747Latent infection of Homo sapiens with Mycobacterium tuberculosis
5893746Phagosomal maturation (early endosomal stage)
5892930Signaling by VEGF
5892891Signal Transduction
5892929VEGFA-VEGFR2 Pathway