LMPD Database

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LMP001370

UniProt Annotations

Entry Information
Gene NameUDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
Protein EntryB3GN2_HUMAN
UniProt IDQ9NY97
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9NY97-1; Sequence=Displayed; Name=2; IsoId=Q9NY97-2; Sequence=VSP_001791; Note=May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. No experimental confirmation available.;
CautionWas indicated as B3Gal-T6 in submitted DNA entries.
CofactorName=Mn(2+); Xref=ChEBI
FunctionCatalyzes the initiation and elongation of poly-N- acetyllactosamine chains.
PathwayProtein modification; protein glycosylation.
Sequence CautionSequence=BAA92031.1; Type=Erroneous initiation; Evidence= ;
SimilarityBelongs to the glycosyltransferase 31 family.
Subcellular LocationGolgi apparatus membrane ; Single-pass type II membrane protein .
SubunitInteracts with B3GNT8; this interaction greatly increases B3GNT2 catalytic activity, independently of B3GNT8 enzymatic activity.
Tissue SpecificityUbiquitous.
Web ResourceName=Functional Glycomics Gateway - GTase; Note=UDP- GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1; URL="http://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_434";
Web ResourceName=GGDB; Note=GlycoGene database; URL="http://jcggdb.jp/rcmg/ggdb/Homolog?cat=symbol&symbol=B3GNT1";