LMPD Database

LMP001316

Gene Information

Entrez Gene ID	13666
Gene Name	eukaryotic translation initiation factor 2 alpha kinase 3
Gene Symbol	Eif2ak3
Species	Mus musculus

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005737	IDA:MGI	C	cytoplasm
GO:0005783	IDA:MGI	C	endoplasmic reticulum
GO:0005789	IDA:MGI	C	endoplasmic reticulum membrane
GO:0005524	IEA:InterPro	F	ATP binding
GO:0004694	IEA:Ensembl	F	eukaryotic translation initiation factor 2alpha kinase activity
GO:0004672	IDA:MGI	F	protein kinase activity
GO:0004674	IDA:MGI	F	protein serine/threonine kinase activity
GO:0006919	IMP:MGI	P	activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0030282	IMP:MGI	P	bone mineralization
GO:0019722	IMP:MGI	P	calcium-mediated signaling
GO:0002063	IMP:MGI	P	chondrocyte development
GO:0031018	IEA:Ensembl	P	endocrine pancreas development
GO:0007029	IMP:MGI	P	endoplasmic reticulum organization
GO:0030968	IDA:MGI	P	endoplasmic reticulum unfolded protein response
GO:0006983	IEA:Ensembl	P	ER overload response
GO:0045444	IDA:MGI	P	fat cell differentiation
GO:0048009	IMP:MGI	P	insulin-like growth factor receptor signaling pathway
GO:0070059	IMP:MGI	P	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0007595	IMP:MGI	P	lactation
GO:0043066	IMP:MGI	P	negative regulation of apoptotic process
GO:0010629	IMP:MGI	P	negative regulation of gene expression
GO:0031642	IMP:MGI	P	negative regulation of myelination
GO:0017148	IDA:MGI	P	negative regulation of translation
GO:0032055	IEA:Ensembl	P	negative regulation of translation in response to stress
GO:0031016	IMP:MGI	P	pancreas development
GO:1902237	IGI:MGI	P	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
GO:0032092	IMP:MGI	P	positive regulation of protein binding
GO:0009967	IDA:MGI	P	positive regulation of signal transduction
GO:0046777	IDA:MGI	P	protein autophosphorylation
GO:0051260	IEA:Ensembl	P	protein homooligomerization
GO:0006468	IDA:MGI	P	protein phosphorylation
GO:0019217	IMP:MGI	P	regulation of fatty acid metabolic process
GO:0001501	IMP:MGI	P	skeletal system development
GO:0032933	IDA:MGI	P	SREBP signaling pathway
GO:0006412	IDA:MGI	P	translation