LMPD Database


UniProt Annotations

Entry Information
Gene NameUDP galactosyltransferase 8A
Protein EntryCGT_MOUSE
UniProt IDQ64676
Comment typeDescription
Catalytic ActivityUDP-alpha-D-galactose + 2-(2- hydroxyacyl)sphingosine = UDP + 1-(beta-D-galactosyl)-2-(2- hydroxyacyl)sphingosine.
FunctionCatalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system.
PathwaySphingolipid metabolism; galactosylceramide biosynthesis.
SimilarityBelongs to the UDP-glycosyltransferase family. {ECO:0000305}.
Subcellular LocationMembrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.