LMPD Database

LMP001247

Gene Information

Entrez Gene ID	5048
Gene Name	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
Gene Symbol	PAFAH1B1
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0000235	IDA:UniProtKB	C	astral microtubule
GO:0005938	IDA:UniProtKB	C	cell cortex
GO:0031252	IEA:Ensembl	C	cell leading edge
GO:0005813	IDA:UniProtKB	C	centrosome
GO:0005829	ISS:BHF-UCL	C	cytosol
GO:0070062	IDA:UniProt	C	extracellular vesicular exosome
GO:0030426	IEA:Ensembl	C	growth cone
GO:0005871	IEA:Ensembl	C	kinesin complex
GO:0000776	IDA:UniProtKB	C	kinetochore
GO:0016020	IEA:UniProtKB-KW	C	membrane
GO:0005875	IDA:UniProtKB	C	microtubule associated complex
GO:0031512	ISS:BHF-UCL	C	motile primary cilium
GO:0043025	IEA:Ensembl	C	neuronal cell body
GO:0005635	IDA:UniProtKB	C	nuclear envelope
GO:0048471	ISS:BHF-UCL	C	perinuclear region of cytoplasm
GO:0034452	ISS:BHF-UCL	F	dynactin binding
GO:0045502	IDA:UniProtKB	F	dynein binding
GO:0008201	ISS:BHF-UCL	F	heparin binding
GO:0008017	ISS:BHF-UCL	F	microtubule binding
GO:0043274	ISS:BHF-UCL	F	phospholipase binding
GO:0051219	ISS:BHF-UCL	F	phosphoprotein binding
GO:0042803	ISS:BHF-UCL	F	protein homodimerization activity
GO:0001675	ISS:BHF-UCL	P	acrosome assembly
GO:0030036	ISS:BHF-UCL	P	actin cytoskeleton organization
GO:0008344	IMP:BHF-UCL	P	adult locomotory behavior
GO:0001667	IEA:Ensembl	P	ameboidal cell migration
GO:0048854	IMP:BHF-UCL	P	brain morphogenesis
GO:0021987	IMP:BHF-UCL	P	cerebral cortex development
GO:0021895	IEA:Ensembl	P	cerebral cortex neuron differentiation
GO:0021540	IMP:BHF-UCL	P	corpus callosum morphogenesis
GO:0051660	IEA:Ensembl	P	establishment of centrosome localization
GO:0000132	IMP:UniProtKB	P	establishment of mitotic spindle orientation
GO:0000086	TAS:Reactome	P	G2/M transition of mitotic cell cycle
GO:0021766	ISS:BHF-UCL	P	hippocampus development
GO:0021819	ISS:BHF-UCL	P	layer formation in cerebral cortex
GO:0007611	ISS:BHF-UCL	P	learning or memory
GO:0016042	IEA:UniProtKB-KW	P	lipid catabolic process
GO:0007017	IDA:UniProtKB	P	microtubule-based process
GO:0000226	ISS:BHF-UCL	P	microtubule cytoskeleton organization
GO:0031023	IMP:UniProtKB	P	microtubule organizing center organization
GO:0000278	TAS:Reactome	P	mitotic cell cycle
GO:0007067	IEA:UniProtKB-KW	P	mitotic nuclear division
GO:0046329	IEA:Ensembl	P	negative regulation of JNK cascade
GO:0010977	IEA:Ensembl	P	negative regulation of neuron projection development
GO:0007405	ISS:BHF-UCL	P	neuroblast proliferation
GO:0050885	IMP:BHF-UCL	P	neuromuscular process controlling balance
GO:0001764	IMP:UniProtKB	P	neuron migration
GO:0051081	IEA:Ensembl	P	nuclear envelope disassembly
GO:0007097	IEA:Ensembl	P	nuclear migration
GO:0036035	IEA:Ensembl	P	osteoclast development
GO:0046469	ISS:BHF-UCL	P	platelet activating factor metabolic process
GO:0045773	IEA:Ensembl	P	positive regulation of axon extension
GO:0001961	IEA:Ensembl	P	positive regulation of cytokine-mediated signaling pathway
GO:0045931	IEA:Ensembl	P	positive regulation of mitotic cell cycle
GO:0009306	IEA:Ensembl	P	protein secretion
GO:0032319	ISS:BHF-UCL	P	regulation of Rho GTPase activity
GO:0008090	ISS:BHF-UCL	P	retrograde axon cargo transport
GO:0017145	IEA:Ensembl	P	stem cell division
GO:0007268	ISS:BHF-UCL	P	synaptic transmission
GO:0019226	ISS:BHF-UCL	P	transmission of nerve impulse
GO:0047496	ISS:BHF-UCL	P	vesicle transport along microtubule

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_160315	Regulation of PLK1 Activity at G2/M Transition
REACT_150471	Separation of Sister Chromatids