LMPD Database

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LMP001138

UniProt Annotations

Entry Information
Gene Namealdehyde dehydrogenase 2, mitochondrial
Protein EntryALDH2_MOUSE
UniProt IDP47738
SpeciesMouse
Comments
Comment typeDescription
Catalytic ActivityAn aldehyde + NAD(+) + H(2)O = a carboxylate + NADH.
FunctionIs capable of converting retinaldehyde to retinoic acid.
InductionBy retinoic acid; 3-5 fold increase.
InteractionQ8R104:Sirt3; NbExp=2; IntAct=EBI-2308120, EBI-6999888;
PathwayAlcohol metabolism; ethanol degradation; acetate from ethanol: step 2/2.
SimilarityBelongs to the aldehyde dehydrogenase family. {ECO:0000305}.
Subcellular LocationMitochondrion matrix.
SubunitHomotetramer. {ECO:0000250}.