LMPD Database

LMP001137

Gene Information

Entrez Gene ID	6256
Gene Name	retinoid X receptor, alpha
Gene Symbol	RXRA
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0000790	IDA:BHF-UCL	C	nuclear chromatin
GO:0005654	TAS:Reactome	C	nucleoplasm
GO:0005634	IDA:UniProtKB	C	nucleus
GO:0004886	TAS:ProtInc	F	9-cis retinoic acid receptor activity
GO:0031490	IEA:Ensembl	F	chromatin DNA binding
GO:0003677	IDA:MGI	F	DNA binding
GO:0019899	IPI:UniProtKB	F	enzyme binding
GO:0004879	IDA:BHF-UCL	F	ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0046982	IDA:UniProtKB	F	protein heterodimerization activity
GO:0003708	TAS:BHF-UCL	F	retinoic acid receptor activity
GO:0044323	IDA:UniProtKB	F	retinoic acid-responsive element binding
GO:0000977	IDA:MGI	F	RNA polymerase II regulatory region sequence-specific DNA binding
GO:0003700	IDA:UniProtKB	F	sequence-specific DNA binding transcription factor activity
GO:0003707	IEA:InterPro	F	steroid hormone receptor activity
GO:0003713	TAS:ProtInc	F	transcription coactivator activity
GO:0042809	IPI:BHF-UCL	F	vitamin D receptor binding
GO:0008270	IEA:InterPro	F	zinc ion binding
GO:0043010	IEA:Ensembl	P	camera-type eye development
GO:0060038	IEA:Ensembl	P	cardiac muscle cell proliferation
GO:0044255	TAS:Reactome	P	cellular lipid metabolic process
GO:0008203	TAS:BHF-UCL	P	cholesterol metabolic process
GO:0007566	IEA:Ensembl	P	embryo implantation
GO:0010467	TAS:Reactome	P	gene expression
GO:0001701	IEA:Ensembl	P	in utero embryonic development
GO:0001893	IEA:Ensembl	P	maternal placenta development
GO:0019048	IDA:UniProtKB	P	modulation by virus of host morphology or physiology
GO:0000122	IDA:BHF-UCL	P	negative regulation of transcription from RNA polymerase II promoter
GO:0035357	IDA:UniProtKB	P	peroxisome proliferator activated receptor signaling pathway
GO:0045944	IDA:UniProtKB	P	positive regulation of transcription from RNA polymerase II promoter
GO:0051289	IDA:MGI	P	protein homotetramerization
GO:0060687	IEA:Ensembl	P	regulation of branching involved in prostate gland morphogenesis
GO:0032526	IMP:BHF-UCL	P	response to retinoic acid
GO:0048384	IMP:BHF-UCL	P	retinoic acid receptor signaling pathway
GO:0060528	IEA:Ensembl	P	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development
GO:0044281	TAS:Reactome	P	small molecule metabolic process
GO:0006367	TAS:Reactome	P	transcription initiation from RNA polymerase II promoter
GO:0055012	IEA:Ensembl	P	ventricular cardiac muscle cell differentiation
GO:0055010	IEA:Ensembl	P	ventricular cardiac muscle tissue morphogenesis
GO:0006766	TAS:ProtInc	P	vitamin metabolic process

KEGG Pathway Links

KEGG Pathway ID	Description
hsa04932	Non-alcoholic fatty liver disease (NAFLD)
hsa04151	PI3K-Akt signaling pathway
hsa04919	Thyroid hormone signaling pathway