LMPD Database

LMP001110

Gene Information

Entrez Gene ID	13982
Gene Name	estrogen receptor 1 (alpha)
Gene Symbol	Esr1
Species	Mus musculus

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005737	IDA:MGI	C	cytoplasm
GO:0005634	IDA:MGI	C	nucleus
GO:0005886	IEA:Ensembl	C	plasma membrane
GO:0003682	IDA:MGI	F	chromatin binding
GO:0001046	IEA:Ensembl	F	core promoter sequence-specific DNA binding
GO:0038052	IEA:Ensembl	F	estrogen-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0034056	IEA:Ensembl	F	estrogen response element binding
GO:0004879	IDA:MGI	F	ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0000978	IEA:Ensembl	F	RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077	IEA:Ensembl	F	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0005496	IEA:UniProtKB-KW	F	steroid binding
GO:0008270	IEA:InterPro	F	zinc ion binding
GO:0008209	IMP:MGI	P	androgen metabolic process
GO:0001547	IMP:MGI	P	antral ovarian follicle growth
GO:0071391	IMP:MGI	P	cellular response to estrogen stimulus
GO:0002064	IMP:MGI	P	epithelial cell development
GO:0060750	IMP:MGI	P	epithelial cell proliferation involved in mammary gland duct elongation
GO:0030522	IDA:GOC	P	intracellular receptor signaling pathway
GO:0008584	IMP:MGI	P	male gonad development
GO:0060749	IMP:MGI	P	mammary gland alveolus development
GO:0060745	IMP:MGI	P	mammary gland branching involved in pregnancy
GO:0010629	IEA:Ensembl	P	negative regulation of gene expression
GO:0043124	IEA:Ensembl	P	negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043433	IEA:Ensembl	P	negative regulation of sequence-specific DNA binding transcription factor activity
GO:0048146	IMP:MGI	P	positive regulation of fibroblast proliferation
GO:0045429	IEA:Ensembl	P	positive regulation of nitric oxide biosynthetic process
GO:0051000	IEA:Ensembl	P	positive regulation of nitric-oxide synthase activity
GO:0048386	IEA:Ensembl	P	positive regulation of retinoic acid receptor signaling pathway
GO:0051091	IEA:Ensembl	P	positive regulation of sequence-specific DNA binding transcription factor activity
GO:0045944	IMP:MGI	P	positive regulation of transcription from RNA polymerase II promoter
GO:0060527	IMP:MGI	P	prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
GO:0060523	IMP:MGI	P	prostate epithelial cord elongation
GO:0042981	IMP:MGI	P	regulation of apoptotic process
GO:0060687	IMP:MGI	P	regulation of branching involved in prostate gland morphogenesis
GO:0006355	IDA:MGI	P	regulation of transcription, DNA-templated
GO:0032355	IEA:Ensembl	P	response to estradiol
GO:0060065	IGI:MGI	P	uterus development
GO:0060068	IGI:MGI	P	vagina development