LMPD Database

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LMP001090

UniProt Annotations

Entry Information
Gene Namecoenzyme Q7 homolog, ubiquinone (yeast)
Protein EntryCOQ7_HUMAN
UniProt IDQ99807
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q99807-1; Sequence=Displayed; Name=2; IsoId=Q99807-2; Sequence=VSP_039068;
CofactorName=Fe cation; Xref=ChEBI
FunctionInvolved in lifespan determination in ubiquinone- independent manner. Involved in ubiquinone biosynthesis. Potential central metabolic regulator (By similarity).
PathwayCofactor biosynthesis; ubiquinone biosynthesis.
SimilarityBelongs to the COQ7 family.
Subcellular LocationMitochondrion inner membrane; Peripheral membrane protein; Matrix side. Note=Synthesized as a preprotein that is imported into the mitochondrial matrix, where the sequence is cleaved off and the mature protein becomes loosely associated with the inner membrane.
SubunitInteracts with ADCK4 and COQ6.
Tissue SpecificityExpressed dominantly in heart and skeletal muscle.