LMPD Database

LMP001083

Record overview

LMPD ID	LMP001083
Gene ID	6258
Species	Homo sapiens (Human)
Gene Name	retinoid X receptor, gamma
Gene Symbol	RXRG
Synonyms	NR2B3; RXRC
Chromosome	1
Map Location	1q22-q23
Summary	This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2010]
Orthologs	View orthologs and multiple alignments for RXRG

Proteins

retinoic acid receptor RXR-gamma isoform a

Refseq ID:	NP_008848
Protein GI:	5902068
UniProt ID:	P48443
mRNA ID:	NM_006917
Length:	463
RefSeq Status:	REVIEWED

MYGNYSHFMKFPAGYGGSPGHTGSTSMSPSAALSTGKPMDSHPSYTDTPVSAPRTLSAVGTPLNALGSPYRVITSAMGPPSGALAAPPGINLVAPPSSQL
NVVNSVSSSEDIKPLPGLPGIGNMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCL
VMGMKREAVQEERQRSRERAESEAECATSGHEDMPVERILEAELAVEPKTESYGDMNMENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVI
LLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYAT
LEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLETPLQIT

retinoic acid receptor RXR-gamma isoform c

Refseq ID:	NP_001243499
Protein GI:	375151577
UniProt ID:	F1T097
mRNA ID:	NM_001256570
Length:	340
RefSeq Status:	REVIEWED

retinoic acid receptor RXR-gamma isoform c
`MNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESE AECATSGHEDMPVERILEAELAVEPKTESYGDMNMENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQD GILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLRL PALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLETPLQIT`

Refseq ID:	NP_001243500
Protein GI:	375151581
UniProt ID:	P48443
mRNA ID:	NM_001256571
Length:	340
RefSeq Status:	REVIEWED

Protein sequence is identical to GI:375151577 (mRNA isoform)