LMPD Database

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LMP001057

UniProt Annotations

Entry Information
Gene Namelanosterol synthase
Protein EntryQ8BLN5_MOUSE
UniProt IDQ8BLN5
SpeciesMouse
Comments
Comment typeDescription
Catalytic Activity(3S)-2,3-epoxy-2,3-dihydrosqualene = lanosterol.
FunctionCatalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus.
PathwayTerpene metabolism; lanosterol biosynthesis; lanosterol from farnesyl diphosphate: step 3/3.
SimilarityBelongs to the terpene cyclase/mutase family.
SimilarityContains 4 PFTB repeats.
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000250}; Peripheral membrane protein .
SubunitMonomer.