LMPD Database

LMP001001

Gene Information

Entrez Gene ID	19401
Gene Name	retinoic acid receptor, alpha
Gene Symbol	Rara
Species	Mus musculus

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005737	IDA:MGI	C	cytoplasm
GO:0030425	IDA:MGI	C	dendrite
GO:0043025	IDA:MGI	C	neuronal cell body
GO:0000790	IEA:Ensembl	C	nuclear chromatin
GO:0005634	IDA:UniProtKB	C	nucleus
GO:0048471	IEA:Ensembl	C	perinuclear region of cytoplasm
GO:0031490	IEA:Ensembl	F	chromatin DNA binding
GO:0003677	IDA:MGI	F	DNA binding
GO:0008144	IEA:Ensembl	F	drug binding
GO:0004879	IDA:MGI	F	ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0048027	IEA:Ensembl	F	mRNA 5'-UTR binding
GO:0035014	IEA:Ensembl	F	phosphatidylinositol 3-kinase regulator activity
GO:0001972	IEA:Ensembl	F	retinoic acid binding
GO:0003708	IDA:MGI	F	retinoic acid receptor activity
GO:0044323	IEA:Ensembl	F	retinoic acid-responsive element binding
GO:0001012	IDA:MGI	F	RNA polymerase II regulatory region DNA binding
GO:0000977	IDA:MGI	F	RNA polymerase II regulatory region sequence-specific DNA binding
GO:0043565	IDA:MGI	F	sequence-specific DNA binding
GO:0003700	IDA:MGI	F	sequence-specific DNA binding transcription factor activity
GO:0003707	IEA:InterPro	F	steroid hormone receptor activity
GO:0003713	IEA:Ensembl	F	transcription coactivator activity
GO:0003714	IEA:Ensembl	F	transcription corepressor activity
GO:0008134	IPI:UniProtKB	F	transcription factor binding
GO:0044212	IMP:UniProtKB	F	transcription regulatory region DNA binding
GO:0000900	IEA:Ensembl	F	translation repressor activity, nucleic acid binding
GO:0008270	IEA:InterPro	F	zinc ion binding
GO:0043277	IEA:Ensembl	P	apoptotic cell clearance
GO:0060348	IGI:MGI	P	bone development
GO:0071391	IEA:Ensembl	P	cellular response to estrogen stimulus
GO:0071222	IDA:UniProtKB	P	cellular response to lipopolysaccharide
GO:0071300	IEA:Ensembl	P	cellular response to retinoic acid
GO:0060591	IMP:MGI	P	chondroblast differentiation
GO:0031076	IGI:MGI	P	embryonic camera-type eye development
GO:0060324	IGI:MGI	P	face development
GO:0007565	IEA:Ensembl	P	female pregnancy
GO:0007281	IMP:UniProtKB	P	germ cell development
GO:0002068	IGI:MGI	P	glandular epithelial cell development
GO:0003417	IGI:MGI	P	growth plate cartilage development
GO:0030520	IEA:Ensembl	P	intracellular estrogen receptor signaling pathway
GO:0060173	IGI:MGI	P	limb development
GO:0001889	IEA:Ensembl	P	liver development
GO:0035264	IGI:MGI	P	multicellular organism growth
GO:0043066	IGI:MGI	P	negative regulation of apoptotic process
GO:0061037	IMP:MGI	P	negative regulation of cartilage development
GO:0045596	IMP:MGI	P	negative regulation of cell differentiation
GO:0008285	IEA:Ensembl	P	negative regulation of cell proliferation
GO:0010629	IGI:MGI	P	negative regulation of gene expression
GO:0030853	IEA:Ensembl	P	negative regulation of granulocyte differentiation
GO:0032689	IEA:Ensembl	P	negative regulation of interferon-gamma production
GO:0045892	IDA:MGI	P	negative regulation of transcription, DNA-templated
GO:0000122	IDA:MGI	P	negative regulation of transcription from RNA polymerase II promoter
GO:0045947	IDA:MGI	P	negative regulation of translational initiation
GO:0032720	IEA:Ensembl	P	negative regulation of tumor necrosis factor production
GO:0001843	IGI:MGI	P	neural tube closure
GO:0003148	IGI:MGI	P	outflow tract septum morphogenesis
GO:0051099	IEA:Ensembl	P	positive regulation of binding
GO:0045787	IEA:Ensembl	P	positive regulation of cell cycle
GO:0008284	IGI:MGI	P	positive regulation of cell proliferation
GO:0070374	IEA:Ensembl	P	positive regulation of ERK1 and ERK2 cascade
GO:0010628	IMP:UniProtKB	P	positive regulation of gene expression
GO:0032736	IEA:Ensembl	P	positive regulation of interleukin-13 production
GO:0032753	IEA:Ensembl	P	positive regulation of interleukin-4 production
GO:0032754	IEA:Ensembl	P	positive regulation of interleukin-5 production
GO:0045666	IEA:Ensembl	P	positive regulation of neuron differentiation
GO:0014068	IEA:Ensembl	P	positive regulation of phosphatidylinositol 3-kinase signaling
GO:0051897	IEA:Ensembl	P	positive regulation of protein kinase B signaling
GO:0045630	IEA:Ensembl	P	positive regulation of T-helper 2 cell differentiation
GO:0045944	IDA:MGI	P	positive regulation of transcription from RNA polymerase II promoter
GO:0030850	IEA:Ensembl	P	prostate gland development
GO:0006468	IEA:Ensembl	P	protein phosphorylation
GO:0030852	IMP:MGI	P	regulation of granulocyte differentiation
GO:0031641	IEA:Ensembl	P	regulation of myelination
GO:0048167	IEA:Ensembl	P	regulation of synaptic plasticity
GO:0006355	IDA:MGI	P	regulation of transcription, DNA-templated
GO:0034097	IEA:Ensembl	P	response to cytokine
GO:0032355	IEA:Ensembl	P	response to estradiol
GO:0045471	IEA:Ensembl	P	response to ethanol
GO:0032526	IMP:MGI	P	response to retinoic acid
GO:0033189	IEA:Ensembl	P	response to vitamin A
GO:0060010	IMP:UniProtKB	P	Sertoli cell fate commitment
GO:0007283	IMP:MGI	P	spermatogenesis
GO:0060534	IMP:MGI	P	trachea cartilage development
GO:0001657	IMP:MGI	P	ureteric bud development
GO:0055012	IMP:MGI	P	ventricular cardiac muscle cell differentiation

KEGG Pathway Links

KEGG Pathway ID	Description
mmu05221	Acute myeloid leukemia