LMPD Database

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LMP000968

UniProt Annotations

Entry Information
Gene NameN(alpha)-acetyltransferase 20, NatB catalytic subunit
Protein EntryNAA20_HUMAN
UniProt IDP61599
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=P61599-1; Sequence=Displayed; Name=2; IsoId=P61599-2; Sequence=VSP_045644; Note=No experimental confirmation available.;
Catalytic ActivityAcetyl-CoA + peptide = N(alpha)-acetylpeptide + CoA.
FunctionCatalytic subunit of the NatB complex which catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Asp, Met-Glu, Met-Asn and Met-Gln. Proteins with cell cycle functions are overrepresented in the pool of NatB substrates. Required for maintaining the structure and function of actomyosin fibers and for proper cellular migration.
Sequence CautionSequence=BG548527; Type=Frameshift; Positions=111; Evidence= ;
SimilarityBelongs to the acetyltransferase family. ARD1 subfamily.
SimilarityContains 1 N-acetyltransferase domain.
Subcellular LocationCytoplasm . Nucleus .
SubunitComponent of the N-terminal acetyltransferase B (NatB) complex which is composed of NAA20 and NAA25.