LMPD Database

LMP000895

Gene Information

Entrez Gene ID11688
Gene Namearachidonate 8-lipoxygenase
Gene SymbolAlox8
SpeciesMus musculus
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005856 IEA:EnsemblCcytoskeleton
GO:0005829 ISS:UniProtKBCcytosol
GO:0019898 IEA:EnsemblCextrinsic component of membrane
GO:0005622 ISS:UniProtKBCintracellular
GO:0005886 IEA:EnsemblCplasma membrane
GO:0050473 IEA:EnsemblFarachidonate 15-lipoxygenase activity
GO:0036403 IDA:UniProtKBFarachidonate 8(S)-lipoxygenase activity
GO:0005509 IEA:EnsemblFcalcium ion binding
GO:0005506 IEA:EnsemblFiron ion binding
GO:0016165 IEA:EnsemblFlinoleate 13S-lipoxygenase activity
GO:0008289 IEA:UniProtKB-KWFlipid binding
GO:0019369 IDA:UniProtKBParachidonic acid metabolic process
GO:0043651 IDA:UniProtKBPlinoleic acid metabolic process
GO:0019372 IDA:UniProtKBPlipoxygenase pathway
GO:0045786 IEA:EnsemblPnegative regulation of cell cycle
GO:0008285 IEA:EnsemblPnegative regulation of cell proliferation
GO:0045926 IEA:EnsemblPnegative regulation of growth
GO:0090197 IEA:EnsemblPpositive regulation of chemokine secretion
GO:0045618 IMP:UniProtKBPpositive regulation of keratinocyte differentiation
GO:0010744 IEA:EnsemblPpositive regulation of macrophage derived foam cell differentiation
GO:0035360 IMP:UniProtKBPpositive regulation of peroxisome proliferator activated receptor signaling pathway
KEGG Pathway Links
KEGG Pathway IDDescription
mmu00590Arachidonic acid metabolism
mmu04726Serotonergic synapse
REACTOME Pathway Links
REACTOME Pathway IDDescription
5894064Synthesis of 15-eicosatetraenoic acid derivatives