LMPD Database

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LMP000772

UniProt Annotations

Entry Information
Gene Namesolute carrier organic anion transporter family, member 2A1
Protein EntrySO2A1_HUMAN
UniProt IDQ92959
SpeciesHuman
Comments
Comment typeDescription
DiseaseHypertrophic osteoarthropathy, primary, autosomal recessive, 2 (PHOAR2) [MIM
FunctionMay mediate the release of newly synthesized prostaglandins from cells, the transepithelial transport of prostaglandins, and the clearance of prostaglandins from the circulation. Transports PGD2, as well as PGE1, PGE2 and PGF2A.
InteractionP62993:GRB2; NbExp=1; IntAct=EBI-1760532, EBI-401755;
SimilarityBelongs to the organo anion transporter (TC 2.A.60) family.
SimilarityContains 1 Kazal-like domain. {ECO
Subcellular LocationCell membrane; Multi-pass membrane protein.
Tissue SpecificityUbiquitous. Significant expression observed in ling, kidney, spleen, and heart.
Web ResourceName=Solute carrier organic anion transporter family, member 2A1 (SLCO2A1); Note=Leiden Open Variation Database (LOVD); URL="http://www.lovd.nl/SLCO2A1";