LMPD Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
LMP000752

UniProt Annotations

Entry Information
Gene Namesterol O-acyltransferase 2
Protein EntrySOAT2_MOUSE
UniProt IDO88908
SpeciesMouse
Comments
Comment typeDescription
Catalytic ActivityAcyl-CoA + cholesterol = CoA + cholesterol ester.
FunctionPlays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase. May provide cholesteryl esters for lipoprotein secretion from hepatocytes and intestinal mucosa.
SimilarityBelongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily. {ECO:0000305}.
Subcellular LocationEndoplasmic reticulum membrane; Multi-pass membrane protein {ECO:0000269|PubMed:11071899}.
SubunitMay form homo- or heterodimers. {ECO:0000250}.