LMPD Database

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LMP000746

UniProt Annotations

Entry Information
Gene Namelysophospholipase 2
Protein EntryLYPA2_MOUSE
UniProt IDQ9WTL7
SpeciesMouse
Comments
Comment typeDescription
Catalytic ActivityPalmitoyl-protein + H(2)O = palmitate + protein.
FunctionMay hydrolyze fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Deacylates GAP43 (By similarity). Has lysophospholipase activity. {ECO:0000250, ECO:0000269|PubMed:10064901}.
SimilarityBelongs to the AB hydrolase superfamily. AB hydrolase 2 family. {ECO:0000305}.
Subcellular LocationCytoplasm {ECO:0000305}.
Tissue SpecificityUbiquitous; detected at low levels. {ECO:0000269|PubMed:10064901}.