LMPD Database

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LMP000646

UniProt Annotations

Entry Information
Gene Nameglucosaminyl (N-acetyl) transferase 2, I-branching enzyme
Protein EntryQ7TPQ8_MOUSE
UniProt IDQ7TPQ8
SpeciesMouse
Comments
Comment typeDescription
Catalytic ActivityUDP-N-acetyl-D-glucosamine + beta-D- galactosyl-1,4-N-acetyl-D-glucosaminyl-R = UDP + N-acetyl-beta-D- glucosaminyl-1,6-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R.
FunctionBranching enzyme that converts linear into branched poly-N-acetyllactosaminoglycans. Introduces the blood group I antigen during embryonic development. It is closely associated with the development and maturation of erythroid cells.
PathwayProtein modification; protein glycosylation.
SimilarityBelongs to the glycosyltransferase 14 family. {ECO:0000305}.
Subcellular LocationGolgi apparatus membrane; Single-pass type II membrane protein.
Web ResourceName=Functional Glycomics Gateway - GTase; Note=Gcnt2 - I branching beta-6-GlcNAcT2, variant 1 (IGnT); URL="http://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_mou_587";
Web ResourceName=Functional Glycomics Gateway - GTase; Note=Gcnt2 - I branching beta-6-GlcNAcT2, variant 3 (IGnT); URL="http://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_mou_563";