LMPD Database

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LMP000596

UniProt Annotations

Entry Information
Gene Namepropionyl Coenzyme A carboxylase, beta polypeptide
Protein EntryPCCB_MOUSE
UniProt IDQ99MN9
SpeciesMouse
Comments
Comment typeDescription
Catalytic ActivityATP + propanoyl-CoA + HCO(3)(-) = ADP + phosphate + (S)-methylmalonyl-CoA.
PathwayMetabolic intermediate metabolism; propanoyl-CoA degradation; succinyl-CoA from propanoyl-CoA: step 1/3.
SimilarityBelongs to the AccD/PCCB family. {ECO:0000305}.
SimilarityContains 1 carboxyltransferase domain. {ECO:0000305}.
Subcellular LocationMitochondrion matrix {ECO:0000250}.
SubunitProbably a dodecamer composed of six biotin-containing alpha subunits and six beta subunits. {ECO:0000250}.
Tissue SpecificityBroadly expressed. Most abundantly expressed in the kidney, liver, small intestine and stomach. {ECO:0000269|PubMed:11245989}.