LMPD Database

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LMP000528

Gene Information

Entrez Gene ID5165
Gene Namepyruvate dehydrogenase kinase, isozyme 3
Gene SymbolPDK3
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005759 TAS:ReactomeCmitochondrial matrix
GO:0005739 TAS:ProtIncCmitochondrion
GO:0005524 IDA:UniProtKBFATP binding
GO:0004672 IDA:UniProtKBFprotein kinase activity
GO:0004674 IDA:UniProtKBFprotein serine/threonine kinase activity
GO:0004740 IDA:UniProtKBFpyruvate dehydrogenase (acetyl-transferring) kinase activity
GO:0008219 IEA:UniProtKB-KWPcell death
GO:0044237 TAS:ReactomePcellular metabolic process
GO:0071398 IMP:UniProtKBPcellular response to fatty acid
GO:0071333 ISS:UniProtKBPcellular response to glucose stimulus
GO:0006006 IEA:UniProtKB-KWPglucose metabolic process
GO:0097411 IMP:UniProtKBPhypoxia-inducible factor-1alpha signaling pathway
GO:0018105 IDA:UniProtKBPpeptidyl-serine phosphorylation
GO:0035357 IMP:UniProtKBPperoxisome proliferator activated receptor signaling pathway
GO:0006090 TAS:ReactomePpyruvate metabolic process
GO:0010510 IMP:UniProtKBPregulation of acetyl-CoA biosynthetic process from pyruvate
GO:0010906 IMP:UniProtKBPregulation of glucose metabolic process
GO:2000377 IMP:UniProtKBPregulation of reactive oxygen species metabolic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_2071Pyruvate metabolism
REACT_1046Pyruvate metabolism and Citric Acid (TCA) cycle
REACT_12528Regulation of pyruvate dehydrogenase (PDH) complex
REACT_111083The citric acid (TCA) cycle and respiratory electron transport