LMPD Database

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LMP000512

Gene Information

Entrez Gene ID5163
Gene Namepyruvate dehydrogenase kinase, isozyme 1
Gene SymbolPDK1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005759 TAS:ReactomeCmitochondrial matrix
GO:0005739 TAS:ProtIncCmitochondrion
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0004672 IDA:UniProtKBFprotein kinase activity
GO:0004674 IEA:UniProtKB-KWFprotein serine/threonine kinase activity
GO:0004740 IDA:UniProtKBFpyruvate dehydrogenase (acetyl-transferring) kinase activity
GO:0008283 IMP:UniProtKBPcell proliferation
GO:0044237 TAS:ReactomePcellular metabolic process
GO:0006006 TAS:ProtIncPglucose metabolic process
GO:0097411 IMP:UniProtKBPhypoxia-inducible factor-1alpha signaling pathway
GO:0008631 IMP:UniProtKBPintrinsic apoptotic signaling pathway in response to oxidative stress
GO:0006468 IDA:GOCPprotein phosphorylation
GO:0006090 TAS:ReactomePpyruvate metabolic process
GO:0010510 TAS:ReactomePregulation of acetyl-CoA biosynthetic process from pyruvate
GO:0010906 IMP:UniProtKBPregulation of glucose metabolic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
KEGG Pathway Links
KEGG Pathway IDDescription
hsa04066HIF-1 signaling pathway