LMPD Database

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LMP000504

Gene Information

Entrez Gene ID246
Gene Namearachidonate 15-lipoxygenase
Gene SymbolALOX15
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 IDA:UniProtKBCcytosol
GO:0031234 IDA:UniProtKBCextrinsic component of cytoplasmic side of plasma membrane
GO:0005811 IDA:UniProtKBClipid particle
GO:0016020 IDA:UniProtKBCmembrane
GO:0005886 ISS:UniProtKBCplasma membrane
GO:0004052 IDA:UniProtKBFarachidonate 12-lipoxygenase activity
GO:0050473 IDA:UniProtKBFarachidonate 15-lipoxygenase activity
GO:0097260 TAS:ReactomeFeoxin A4 synthase activity
GO:0005506 ISS:UniProtKBFiron ion binding
GO:0005546 IDA:UniProtKBFphosphatidylinositol-4,5-bisphosphate binding
GO:0043277 ISS:UniProtKBPapoptotic cell clearance
GO:0019369 IDA:UniProtKBParachidonic acid metabolic process
GO:0030282 ISS:UniProtKBPbone mineralization
GO:0071277 IDA:UniProtKBPcellular response to calcium ion
GO:0035963 IMP:UniProtKBPcellular response to interleukin-13
GO:0051122 ISS:UniProtKBPhepoxilin biosynthetic process
GO:0006954 TAS:ProtIncPinflammatory response
GO:0006691 TAS:ReactomePleukotriene metabolic process
GO:2001303 ISS:UniProtKBPlipoxin A4 biosynthetic process
GO:0019372 IDA:UniProtKBPlipoxygenase pathway
GO:0002820 ISS:UniProtKBPnegative regulation of adaptive immune response
GO:0001503 ISS:UniProtKBPossification
GO:0006646 ISS:UniProtKBPphosphatidylethanolamine biosynthetic process
GO:0030838 ISS:UniProtKBPpositive regulation of actin filament polymerization
GO:0010811 IDA:UniProtKBPpositive regulation of cell-substrate adhesion
GO:0070374 IMP:UniProtKBPpositive regulation of ERK1 and ERK2 cascade
GO:1901074 ISS:UniProtKBPregulation of engulfment of apoptotic cell
GO:0035358 ISS:UniProtKBPregulation of peroxisome proliferator activated receptor signaling pathway
GO:0034976 ISS:UniProtKBPresponse to endoplasmic reticulum stress
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0042060 ISS:UniProtKBPwound healing
KEGG Pathway Links
KEGG Pathway IDDescription
hsa04726Serotonergic synapse
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_150201Synthesis of 12-eicosatetraenoic acid derivatives
REACT_150422Synthesis of 15-eicosatetraenoic acid derivatives