LMPD Database

LMP000490

Gene Information

Entrez Gene ID	1594
Gene Name	cytochrome P450, family 27, subfamily B, polypeptide 1
Gene Symbol	CYP27B1
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005737	IDA:BHF-UCL	C	cytoplasm
GO:0005741	TAS:Reactome	C	mitochondrial outer membrane
GO:0005739	ISS:BHF-UCL	C	mitochondrion
GO:0004498	IDA:BHF-UCL	F	calcidiol 1-monooxygenase activity
GO:0020037	IEA:InterPro	F	heme binding
GO:0005506	IEA:InterPro	F	iron ion binding
GO:0030282	IEP:BHF-UCL	P	bone mineralization
GO:0036378	IDA:BHF-UCL	P	calcitriol biosynthetic process from calciol
GO:0055074	IMP:BHF-UCL	P	calcium ion homeostasis
GO:0006816	ISS:BHF-UCL	P	calcium ion transport
GO:0046697	IEP:BHF-UCL	P	decidualization
GO:0070314	IMP:BHF-UCL	P	G1 to G0 transition
GO:0010956	IDA:BHF-UCL	P	negative regulation of calcidiol 1-monooxygenase activity
GO:0030308	IMP:BHF-UCL	P	negative regulation of cell growth
GO:0008285	IDA:BHF-UCL	P	negative regulation of cell proliferation
GO:0045618	IMP:BHF-UCL	P	positive regulation of keratinocyte differentiation
GO:0010980	IDA:BHF-UCL	P	positive regulation of vitamin D 24-hydroxylase activity
GO:0070564	IDA:BHF-UCL	P	positive regulation of vitamin D receptor signaling pathway
GO:0030500	IMP:BHF-UCL	P	regulation of bone mineralization
GO:0043627	IEP:BHF-UCL	P	response to estrogen
GO:0034341	IDA:BHF-UCL	P	response to interferon-gamma
GO:0032496	IDA:BHF-UCL	P	response to lipopolysaccharide
GO:0033280	IDA:BHF-UCL	P	response to vitamin D
GO:0044281	TAS:Reactome	P	small molecule metabolic process
GO:0008202	TAS:Reactome	P	steroid metabolic process
GO:0042369	IEA:Ensembl	P	vitamin D catabolic process
GO:0042359	IDA:BHF-UCL	P	vitamin D metabolic process
GO:0006766	TAS:Reactome	P	vitamin metabolic process
GO:0006805	TAS:Reactome	P	xenobiotic metabolic process

KEGG Pathway Links

KEGG Pathway ID	Description
hsa05152	Tuberculosis

BIOCYC Pathway Links

BIOCYC Pathway ID	Description
PWY-6076	1,25-dihydroxyvitamin D3 biosynthesis