LMPD Database

LMP000468

Gene Information

Entrez Gene ID	5294
Gene Name	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
Gene Symbol	PIK3CG
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005737	IDA:UniProtKB	C	cytoplasm
GO:0005829	TAS:Reactome	C	cytosol
GO:0042629	TAS:GOC	C	mast cell granule
GO:0016020	IDA:UniProtKB	C	membrane
GO:0005944	IDA:UniProtKB	C	phosphatidylinositol 3-kinase complex, class IB
GO:0005886	IBA:RefGenome	C	plasma membrane
GO:0016303	IBA:RefGenome	F	1-phosphatidylinositol-3-kinase activity
GO:0035005	IBA:RefGenome	F	1-phosphatidylinositol-4-phosphate 3-kinase activity
GO:0005524	IEA:UniProtKB-KW	F	ATP binding
GO:0046875	IPI:UniProtKB	F	ephrin receptor binding
GO:0035004	TAS:UniProtKB	F	phosphatidylinositol 3-kinase activity
GO:0046934	IBA:RefGenome	F	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0004672	TAS:UniProtKB	F	protein kinase activity
GO:0004674	IEA:UniProtKB-KW	F	protein serine/threonine kinase activity
GO:0002250	TAS:UniProtKB	P	adaptive immune response
GO:0001525	IEA:UniProtKB-KW	P	angiogenesis
GO:0007596	TAS:Reactome	P	blood coagulation
GO:0001816	TAS:UniProtKB	P	cytokine production
GO:0002407	TAS:UniProtKB	P	dendritic cell chemotaxis
GO:0006897	IEA:UniProtKB-KW	P	endocytosis
GO:0007186	IDA:UniProtKB	P	G-protein coupled receptor signaling pathway
GO:0097284	IEA:Ensembl	P	hepatocyte apoptotic process
GO:0006954	TAS:UniProtKB	P	inflammatory response
GO:0045087	TAS:UniProtKB	P	innate immune response
GO:0043303	TAS:UniProtKB	P	mast cell degranulation
GO:0035747	TAS:UniProtKB	P	natural killer cell chemotaxis
GO:0055118	TAS:UniProtKB	P	negative regulation of cardiac muscle contraction
GO:2000270	IEA:Ensembl	P	negative regulation of fibroblast apoptotic process
GO:0010897	IEA:Ensembl	P	negative regulation of triglyceride catabolic process
GO:0030593	TAS:UniProtKB	P	neutrophil chemotaxis
GO:0072672	TAS:UniProtKB	P	neutrophil extravasation
GO:0014065	IDA:UniProtKB	P	phosphatidylinositol 3-kinase signaling
GO:0006661	TAS:Reactome	P	phosphatidylinositol biosynthetic process
GO:0006644	TAS:Reactome	P	phospholipid metabolic process
GO:0030168	TAS:Reactome	P	platelet activation
GO:0070527	TAS:UniProtKB	P	platelet aggregation
GO:0002675	IEA:Ensembl	P	positive regulation of acute inflammatory response
GO:0007204	IEA:Ensembl	P	positive regulation of cytosolic calcium ion concentration
GO:0043406	IDA:UniProtKB	P	positive regulation of MAP kinase activity
GO:0051897	IDA:UniProtKB	P	positive regulation of protein kinase B signaling
GO:0033628	TAS:UniProtKB	P	regulation of cell adhesion mediated by integrin
GO:0002679	TAS:UniProtKB	P	respiratory burst involved in defense response
GO:0032252	IEA:Ensembl	P	secretory granule localization
GO:0044281	TAS:Reactome	P	small molecule metabolic process
GO:0042110	TAS:UniProtKB	P	T cell activation
GO:0010818	TAS:UniProtKB	P	T cell chemotaxis
GO:0042098	TAS:UniProtKB	P	T cell proliferation

KEGG Pathway Links

KEGG Pathway ID	Description
hsa04152	AMPK signaling pathway
hsa04024	cAMP signaling pathway
hsa04022	cGMP-PKG signaling pathway
hsa04550	Signaling pathways regulating pluripotency of stem cells