LMPD Database

LMP000426

Gene Information

Entrez Gene ID	5467
Gene Name	peroxisome proliferator-activated receptor delta
Gene Symbol	PPARD
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005654	TAS:Reactome	C	nucleoplasm
GO:0005634	NAS:UniProtKB	C	nucleus
GO:0003677	ISS:UniProtKB	F	DNA binding
GO:0008144	IDA:UniProtKB	F	drug binding
GO:0004879	IDA:UniProtKB	F	ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0070539	IDA:UniProtKB	F	linoleic acid binding
GO:0008289	IDA:UniProtKB	F	lipid binding
GO:0043565	IEA:InterPro	F	sequence-specific DNA binding
GO:0003700	IDA:UniProtKB	F	sequence-specific DNA binding transcription factor activity
GO:0003707	TAS:ProtInc	F	steroid hormone receptor activity
GO:0003713	IEA:Ensembl	F	transcription coactivator activity
GO:0008270	IEA:InterPro	F	zinc ion binding
GO:0060612	IEA:Ensembl	P	adipose tissue development
GO:0042640	IEA:Ensembl	P	anagen
GO:0097190	IMP:UniProtKB	P	apoptotic signaling pathway
GO:0008366	ISS:UniProtKB	P	axon ensheathment
GO:0030154	IEA:Ensembl	P	cell differentiation
GO:0008283	ISS:UniProtKB	P	cell proliferation
GO:0031589	IEA:Ensembl	P	cell-substrate adhesion
GO:0071456	IEA:Ensembl	P	cellular response to hypoxia
GO:0008203	TAS:UniProtKB	P	cholesterol metabolic process
GO:0046697	TAS:UniProtKB	P	decidualization
GO:0007566	TAS:UniProtKB	P	embryo implantation
GO:0006635	ISS:UniProtKB	P	fatty acid beta-oxidation
GO:0009062	TAS:UniProtKB	P	fatty acid catabolic process
GO:0015908	ISS:UniProtKB	P	fatty acid transport
GO:0010467	TAS:Reactome	P	gene expression
GO:0006091	TAS:ProtInc	P	generation of precursor metabolites and energy
GO:0006006	NAS:UniProtKB	P	glucose metabolic process
GO:0015758	NAS:UniProtKB	P	glucose transport
GO:0007507	IEA:Ensembl	P	heart development
GO:0030522	IDA:GOC	P	intracellular receptor signaling pathway
GO:0051546	IEA:Ensembl	P	keratinocyte migration
GO:0043616	IEA:Ensembl	P	keratinocyte proliferation
GO:0006629	ISS:UniProtKB	P	lipid metabolic process
GO:0009299	IEA:Ensembl	P	mRNA transcription
GO:0043066	IEA:Ensembl	P	negative regulation of apoptotic process
GO:0030308	IEA:Ensembl	P	negative regulation of cell growth
GO:0032966	IEA:Ensembl	P	negative regulation of collagen biosynthetic process
GO:0050680	IEA:Ensembl	P	negative regulation of epithelial cell proliferation
GO:0050728	IEA:Ensembl	P	negative regulation of inflammatory response
GO:0014912	IEA:Ensembl	P	negative regulation of smooth muscle cell migration
GO:0048662	IEA:Ensembl	P	negative regulation of smooth muscle cell proliferation
GO:0045892	ISS:UniProtKB	P	negative regulation of transcription, DNA-templated
GO:0000122	ISS:UniProtKB	P	negative regulation of transcription from RNA polymerase II promoter
GO:0008654	IEA:Ensembl	P	phospholipid biosynthetic process
GO:0008284	IEA:Ensembl	P	positive regulation of cell proliferation
GO:0045684	IEA:Ensembl	P	positive regulation of epidermis development
GO:0045600	NAS:UniProtKB	P	positive regulation of fat cell differentiation
GO:0032024	IEA:Ensembl	P	positive regulation of insulin secretion
GO:0014068	IEA:Ensembl	P	positive regulation of phosphatidylinositol 3-kinase signaling
GO:0045893	IDA:UniProtKB	P	positive regulation of transcription, DNA-templated
GO:0045909	IEA:Ensembl	P	positive regulation of vasodilation
GO:0006029	IEA:Ensembl	P	proteoglycan metabolic process
GO:0006357	TAS:ProtInc	P	regulation of transcription from RNA polymerase II promoter
GO:0014823	IEA:Ensembl	P	response to activity
GO:0009749	IEA:Ensembl	P	response to glucose
GO:0033189	IEA:Ensembl	P	response to vitamin A
GO:0006367	TAS:Reactome	P	transcription initiation from RNA polymerase II promoter
GO:0006776	IEA:Ensembl	P	vitamin A metabolic process
GO:0042060	IEA:Ensembl	P	wound healing

KEGG Pathway Links

KEGG Pathway ID	Description
hsa05221	Acute myeloid leukemia