LMPD Database

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LMP000420

Gene Information

Entrez Gene ID8394
Gene Namephosphatidylinositol-4-phosphate 5-kinase, type I, alpha
Gene SymbolPIP5K1A
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:HPACcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0005925 IDA:UniProtKBCfocal adhesion
GO:0030027 IDA:UniProtKBClamellipodium
GO:0016607 IDA:UniProtKBCnuclear speck
GO:0005634 IDA:UniProtKBCnucleus
GO:0005886 IDA:UniProtKBCplasma membrane
GO:0032587 IDA:UniProtKBCruffle membrane
GO:0016308 IDA:UniProtKBF1-phosphatidylinositol-4-phosphate 5-kinase activity
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0019900 IDA:UniProtKBFkinase binding
GO:0031532 IMP:UniProtKBPactin cytoskeleton reorganization
GO:0032863 IMP:UniProtKBPactivation of Rac GTPase activity
GO:0060326 IMP:UniProtKBPcell chemotaxis
GO:0016477 NAS:UniProtKBPcell migration
GO:0010761 IEA:EnsemblPfibroblast migration
GO:0048041 IMP:UniProtKBPfocal adhesion assembly
GO:0006650 TAS:ProtIncPglycerophospholipid metabolic process
GO:0030216 TAS:UniProtKBPkeratinocyte differentiation
GO:0006909 TAS:UniProtKBPphagocytosis
GO:0006661 TAS:ReactomePphosphatidylinositol biosynthetic process
GO:0046854 IDA:GOCPphosphatidylinositol phosphorylation
GO:0008654 IDA:UniProtKBPphospholipid biosynthetic process
GO:0006644 TAS:ReactomePphospholipid metabolic process
GO:0072661 IMP:UniProtKBPprotein targeting to plasma membrane
GO:0097178 IMP:UniProtKBPruffle assembly
GO:0007165 TAS:ProtIncPsignal transduction
GO:0044281 TAS:ReactomePsmall molecule metabolic process
KEGG Pathway Links
KEGG Pathway IDDescription
hsa04144Endocytosis
hsa04666Fc gamma R-mediated phagocytosis
BIOCYC Pathway Links
BIOCYC Pathway IDDescription
PWY-6351D-myo-inositol (1,4,5)-trisphosphate biosynthesis
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_121025Synthesis of PIPs at the plasma membrane