LMPD Database

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LMP000404

UniProt Annotations

Entry Information
Gene Nameperoxisomal trans-2-enoyl-CoA reductase
Protein EntryPECR_HUMAN
UniProt IDQ9BY49
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9BY49-1; Sequence=Displayed; Name=2; IsoId=Q9BY49-2; Sequence=VSP_013260;
Catalytic ActivityAcyl-CoA + NADP(+) = trans-2,3-dehydroacyl-CoA + NADPH.
FunctionParticipates in chain elongation of fatty acids. Has no 2,4-dienoyl-CoA reductase activity.
InductionNot induced by IR.
PathwayLipid metabolism; fatty acid biosynthesis.
Sequence CautionSequence=AAF69798.1; Type=Erroneous initiation; Evidence= ;
SimilarityBelongs to the short-chain dehydrogenases/reductases (SDR) family.
Subcellular LocationPeroxisome .
SubunitInteracts with PEX5, probably required to target it into peroxisomes.