LMPD Database

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LMP000363

UniProt Annotations

Entry Information
Gene Nameglycerol phosphate dehydrogenase 2, mitochondrial
Protein EntryGPDM_MOUSE
UniProt IDQ64521
SpeciesMouse
Comments
Comment typeDescription
Catalytic Activitysn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.
CofactorName=FAD; Xref=ChEBI:CHEBI:57692;
Enzyme RegulationCalcium-binding enhance the activity of the enzyme.
PathwayPolyol metabolism; glycerol degradation via glycerol kinase pathway; glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route): step 1/1.
SimilarityBelongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. {ECO:0000305}.
SimilarityContains 2 EF-hand domains. {ECO:0000255|PROSITE- ProRule:PRU00448}.
Subcellular LocationMitochondrion inner membrane.