LMPD Database

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LMP000343

UniProt Annotations

Entry Information
Gene Namesolute carrier family 25 (mitochondrial carrier, palmitoylcarnitine transporter), member 29
Protein EntryMCATL_MOUSE
UniProt IDQ8BL03
SpeciesMouse
Comments
Comment typeDescription
FunctionTransports arginine, lysine, homoarginine, methylarginine and, to a much lesser extent, ornithine and histidine. Does not transport carnitine nor acylcarnitines. Functions by both counter-exchange and uniport mechanisms (By similarity). {ECO:0000250}.
InductionBy partial hepactectomy and fasting. {ECO:0000269|PubMed:12882971}.
SimilarityBelongs to the mitochondrial carrier (TC 2.A.29) family. {ECO:0000305}.
SimilarityContains 3 Solcar repeats. {ECO:0000255|PROSITE- ProRule:PRU00282}.
Subcellular LocationMitochondrion inner membrane {ECO:0000269|PubMed:12882971, ECO:0000269|PubMed:19287344}; Multi- pass membrane protein {ECO:0000269|PubMed:12882971, ECO:0000269|PubMed:19287344}.
Tissue SpecificityWidely expressed, with highest levels in the brain, including cortex, cerebellum, hippocampus and hypothalamus, and moderate levels in liver, kidney, heart and testis. {ECO:0000269|PubMed:12882971, ECO:0000269|PubMed:19287344}.