LMPD Database

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LMP000331

Gene Information

Entrez Gene ID18750
Gene Nameprotein kinase C, alpha
Gene SymbolPrkca
SpeciesMus musculus
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0045177 IDA:MGICapical part of cell
GO:0005737 IDA:MGICcytoplasm
GO:0030425 IDA:MGICdendrite
GO:0005739 IDA:MGICmitochondrion
GO:0043025 IDA:MGICneuronal cell body
GO:0005634 IDA:MGICnucleus
GO:0048471 ISS:UniProtKBCperinuclear region of cytoplasm
GO:0001750 IDA:MGICphotoreceptor outer segment
GO:0005886 IDA:MGICplasma membrane
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0004698 IDA:MGIFcalcium-dependent protein kinase C activity
GO:0004697 IDA:MGIFprotein kinase C activity
GO:0004674 IDA:MGIFprotein serine/threonine kinase activity
GO:0008270 IEA:InterProFzinc ion binding
GO:0001525 IEA:UniProtKB-KWPangiogenesis
GO:0007155 IEA:UniProtKB-KWPcell adhesion
GO:0006874 IMP:MGIPcellular calcium ion homeostasis
GO:0071322 IDA:MGIPcellular response to carbohydrate stimulus
GO:0002062 IDA:MGIPchondrocyte differentiation
GO:0000188 IMP:MGIPinactivation of MAPK activity
GO:0050930 IMP:MGIPinduction of positive chemotaxis
GO:0097193 IMP:MGIPintrinsic apoptotic signaling pathway
GO:0008285 IGI:MGIPnegative regulation of cell proliferation
GO:0034351 ISS:UniProtKBPnegative regulation of glial cell apoptotic process
GO:0046325 IMP:MGIPnegative regulation of glucose import
GO:0046627 IMP:MGIPnegative regulation of insulin receptor signaling pathway
GO:0006469 IMP:MGIPnegative regulation of protein kinase activity
GO:0001933 IMP:MGIPnegative regulation of protein phosphorylation
GO:0030593 IMP:MGIPneutrophil chemotaxis
GO:0036289 IDA:MGIPpeptidyl-serine autophosphorylation
GO:0045766 ISS:UniProtKBPpositive regulation of angiogenesis
GO:0010613 ISS:UniProtKBPpositive regulation of cardiac muscle hypertrophy
GO:0045785 ISS:UniProtKBPpositive regulation of cell adhesion
GO:0030335 ISS:UniProtKBPpositive regulation of cell migration
GO:2000707 IMP:UniProtKBPpositive regulation of dense core granule biogenesis
GO:0010595 ISS:UniProtKBPpositive regulation of endothelial cell migration
GO:0001938 ISS:UniProtKBPpositive regulation of endothelial cell proliferation
GO:0070374 ISS:UniProtKBPpositive regulation of ERK1 and ERK2 cascade
GO:0050729 IMP:MGIPpositive regulation of inflammatory response
GO:0031666 ISS:UniProtKBPpositive regulation of lipopolysaccharide-mediated signaling pathway
GO:0045651 IMP:UniProtKBPpositive regulation of macrophage differentiation
GO:0045931 ISS:UniProtKBPpositive regulation of mitotic cell cycle
GO:0001934 IMP:MGIPpositive regulation of protein phosphorylation
GO:0006468 IDA:MGIPprotein phosphorylation
GO:0006937 IMP:MGIPregulation of muscle contraction
GO:0050730 IMP:MGIPregulation of peptidyl-tyrosine phosphorylation
GO:0090330 IMP:UniProtKBPregulation of platelet aggregation
GO:0002026 IMP:MGIPregulation of the force of heart contraction
KEGG Pathway Links
KEGG Pathway IDDescription
mmu04261Adrenergic signaling in cardiomyocytes
mmu04750Inflammatory mediator regulation of TRP channels
mmu04921Oxytocin signaling pathway
mmu04919Thyroid hormone signaling pathway