LMPD Database

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LMP000266

UniProt Annotations

Entry Information
Gene Namealdo-keto reductase family 1, member E1
Protein EntryAKCL2_MOUSE
UniProt IDQ9DCT1
SpeciesMouse
Comments
Comment typeDescription
Biophysicochemical PropertiesKinetic parameters: KM=1.02 mM for 1,5-anhydro-D-fructose {ECO:0000269|PubMed:18323634}; Vmax=0.57 umol/min/mg enzyme {ECO:0000269|PubMed:18323634};
Catalytic Activity1,5-anhydro-D-glucitol + NADP(+) = 1,5- anhydro-D-fructose + NADPH. {ECO:0000269|PubMed:18323634}.
FunctionCatalyzes the NADPH-dependent reduction of 1,5-anhydro- D-fructose (AF) to 1,5-anhydro-D-glucitol. Can also catalyze the reduction of various aldehydes and quinones.
SimilarityBelongs to the aldo/keto reductase family. {ECO:0000305}.
Subcellular LocationCytoplasm.