LMPD Database

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LMP000253

UniProt Annotations

Entry Information
Gene NameUDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
Protein EntryB3GT5_MOUSE
UniProt IDQ9JI67
SpeciesMouse
Comments
Comment typeDescription
FunctionCatalyzes the transfer of Gal to GlcNAc-based acceptors with a preference for the core3 O-linked glycan GlcNAc(beta1,3)GalNAc structure. Can use glycolipid LC3Cer as an efficient acceptor. Also catalyzes the transfer of Gal to the terminal GalNAc unit of the globoside GB4, thereby synthesizing the glycolipid GB5, also known as the stage-specific embryonic antigen-3 (SSEA-3).
PathwayProtein modification; protein glycosylation.
SimilarityBelongs to the glycosyltransferase 31 family. {ECO:0000305}.
Subcellular LocationGolgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Tissue SpecificityExpressed in brain and kidney.
Web ResourceName=Functional Glycomics Gateway - GTase; Note=b3GalT5; URL="http://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_mou_458";