LMPD Database

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LMP000228

UniProt Annotations

Entry Information
Gene Namefucosyltransferase 4
Protein EntryFUT4_MOUSE
UniProt IDQ11127
SpeciesMouse
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=Long; IsoId=Q11127-1; Sequence=Displayed; Name=Short; IsoId=Q11127-2; Sequence=VSP_001778;
FunctionMay catalyze alpha-1,3 glycosidic linkages involved in the expression of Lewis X/SSEA-1 and VIM-2 antigens.
PathwayProtein modification; protein glycosylation.
SimilarityBelongs to the glycosyltransferase 10 family. {ECO:0000305}.
Subcellular LocationGolgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Tissue SpecificityHighest expression in stomach and colon. It is also expressed in the lung, testis, uterus, small intestine and to a lesser extent in spleen, and ovary. Present in trace amounts in brain, thymus, heart, smooth muscle, kidney and bone marrow. Not found in liver, salivary gland and pancreas.
Web ResourceName=Functional Glycomics Gateway - GTase; Note=Fucosyltransferase 4; URL="http://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_mou_613";