LMPD Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
LMP000225

UniProt Annotations

Entry Information
Gene Namemacrophage scavenger receptor 1
Protein EntryQ8CED7_MOUSE
UniProt IDQ8CED7
SpeciesMouse
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=I; IsoId=P30204-1; Sequence=Displayed; Name=II; IsoId=P30204-2; Sequence=VSP_006231, VSP_006232;
FunctionMembrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL).
Sequence CautionSequence=AAA39747.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAA39748.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
SimilarityContains 1 collagen-like domain. {ECO:0000305}.
SimilarityContains 1 SRCR domain. {ECO:0000255|PROSITE- ProRule:PRU00196}.
Subcellular LocationMembrane; Single-pass type II membrane protein.
SubunitHomotrimer.