LMPD Database

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LMP000191

UniProt Annotations

Entry Information
Gene Namelipase, hepatic
Protein EntryLIPC_MOUSE
UniProt IDP27656
SpeciesMouse
Comments
Comment typeDescription
Catalytic ActivityTriacylglycerol + H(2)O = diacylglycerol + a carboxylate.
FunctionHepatic lipase has the capacity to catalyze hydrolysis of phospholipids, mono-, di-, and triglycerides, and acyl-CoA thioesters. It is an important enzyme in HDL metabolism. Hepatic lipase binds heparin.
SimilarityBelongs to the AB hydrolase superfamily. Lipase family. {ECO:0000305}.
SimilarityContains 1 PLAT domain. {ECO:0000255|PROSITE- ProRule:PRU00152}.
Subcellular LocationSecreted.