LMPD Database

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LMP000187

UniProt Annotations

Entry Information
Gene Nameretinoid X receptor beta
Protein EntryQ8VCR0_MOUSE
UniProt IDQ8VCR0
SpeciesMouse
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Comment=Additional isoforms seem to exist.; Name=Long; IsoId=P28704-1; Sequence=Displayed; Name=Short; IsoId=P28704-2; Sequence=VSP_003678;
DomainComposed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
FunctionNuclear hormone receptor. Involved in the retinoic acid response pathway. Binds 9-cis retinoic acid (9C-RA). Binds to both, class I regulatory element of major histocompatibility class I genes (CRE) and the estrogen response element (ERE).
SimilarityBelongs to the nuclear hormone receptor family. NR2 subfamily. {ECO:0000305}.
SimilarityContains 1 nuclear receptor DNA-binding domain. {ECO:0000255|PROSITE-ProRule:PRU00407}.
Subcellular LocationNucleus.
Tissue SpecificityIn all tissues tested including brain, thymus spleen and liver.