Microarray analysis of bone marrow-derived macrophage cells treated with Kdo₂-lipid A (KLA) and ATP

Kdo₂-Lipid A / ATP gene array data - treatment:control ratios

KEGG pathway: Ubiquinone and other terpenoid-quinone biosynthesis (mmu00130)

Legend: : View data/graphs for replicates

Gene symbol	Time course plot	Accession	Description	Treatment	15min	30min	1hr	2hr	4hr	8hr	20hr
Coq2	KLA  ATP  ATP+KLA	NM_027978	coenzyme Q2 homolog, prenyltransferase (yeast) (Coq2), mRNA [NM_027978]	KLA	.94	.98	1.00	.84	.87	.84	.96
				ATP	1.05	.97	1.18	.86	.67	.48	.60
				KLA/ATP	.96	1.03	1.20	.81	.67	.58	.64
Coq3	KLA  ATP  ATP+KLA	NM_172687	coenzyme Q3 homolog, methyltransferase (yeast) (Coq3), mRNA [NM_172687]	KLA	.99	.93	.95	.84	.81	.85	1.04
				ATP	1.02	1.06	.91	.90	.74	.77	.88
				KLA/ATP	1.02	1.08	.83	.85	.73	.75	.87
Coq5	KLA  ATP  ATP+KLA	NM_026504	coenzyme Q5 homolog, methyltransferase (yeast) (Coq5), mRNA [NM_026504]	KLA	.94	.96	1.00	1.10	1.24	1.27	1.36
				ATP	.94	.95	.91	.98	.75	.63	1.01
				KLA/ATP	.93	.97	1.02	1.00	.87	.74	.90
Coq6	KLA  ATP  ATP+KLA	NM_172582	coenzyme Q6 homolog (yeast) (Coq6), mRNA [NM_172582]	KLA	1.02	1.14	1.11	1.07	.94	.78	1.01
				ATP	1.06	1.14	.99	1.34	1.08	.63	.79
				KLA/ATP	1.09	1.29	1.02	1.21	.93	.73	.76
Coq7	KLA  ATP  ATP+KLA	NM_009940	demethyl-Q 7 (Coq7), mRNA [NM_009940]	KLA	.99	1.01	.91	.99	.88	.91	1.25
				ATP	.98	.95	1.19	1.19	1.06	.99	.87
				KLA/ATP	.98	.99	1.24	1.14	1.08	.95	.71
Ggcx	KLA  ATP  ATP+KLA	NM_019802	gamma-glutamyl carboxylase (Ggcx), mRNA [NM_019802]	KLA	1.00	1.00	.97	.95	.86	.92	.89
				ATP	1.12	1.24	1.17	1.14	.81	.74	.88
				KLA/ATP	1.11	1.02	.86	1.10	.76	.78	.80
Hpd	KLA  ATP  ATP+KLA	NM_008277	4-hydroxyphenylpyruvic acid dioxygenase (Hpd), mRNA [NM_008277]	KLA	.94	1.10	1.04	1.02	.97	.97	1.06
				ATP	1.05	1.07	.96	1.01	1.09	.97	1.01
				KLA/ATP	1.02	1.03	1.12	1.00	.98	1.06	1.02
Mm.5662	KLA  ATP  ATP+KLA	27369991	Unknown	KLA	1.04	1.09	.90	.88	.75	.70	1.19
				ATP	1.09	1.21	.84	.88	.57	.63	.90
				KLA/ATP	1.08	1.06	.73	.89	.61	.60	.72
Nqo1	KLA  ATP  ATP+KLA	NM_008706	NAD(P)H dehydrogenase, quinone 1 (Nqo1), mRNA [NM_008706]	KLA	1.04	1.04	.96	.82	.63	.55	.46
				ATP	1.00	1.00	1.04	1.02	1.21	8.72	14.20
				KLA/ATP	.96	1.00	.97	.89	.81	2.66	8.05
Tat	KLA  ATP  ATP+KLA	NM_146214	tyrosine aminotransferase (Tat), nuclear gene encoding mitochondrial protein, mRNA [NM_146214]	KLA	1.13	1.09	1.19	1.17	1.14	1.19	1.10
				ATP	.97	1.08	1.12	1.25	1.02	1.16	1.18
				KLA/ATP	1.16	1.21	1.27	1.23	1.22	1.11	1.08
Vkorc1	KLA  ATP  ATP+KLA	NM_178600	vitamin K epoxide reductase complex, subunit 1 (Vkorc1), mRNA [NM_178600]	KLA	.84	.77	.83	.78	.71	.61	.41
				ATP	1.10	1.03	1.31	1.28	1.10	.93	.65
				KLA/ATP	.95	.88	1.15	1.06	.93	.75	.55