Sphingoid bases
Class abbreviations
| Common Name | Lipid Class | Abbreviation |
|---|---|---|
| Sphingoid bases | Sphingoid bases | SPB |
| Sphingoid base-phosphates | Sphingoid bases | SPBP |
| Lysoinositolphosphorylceramides | Lysoceramide phosphoinositols | LIPC |
| Lysosphingomyelin | Lysosphingomyelins and lysoglycosphingolipids | LSM |
Specific rules for sphingoid bases (SPB)
- The sum composition of sphingoid base and fatty acid is shown as number of C-atoms:DBE;O-atoms, e.g. SPB 34:1;O2.
- Double bond geometry is annotated in parenthesis, e.g. SPB 34:1(4E);O2.
- When the number of hydroxyl groups on SPB is not known, e.g. for mammals, two hydroxyl groups are assumed.
- Sphingoid base phosphates with unknown phosphate position are represented by SPBP, e.g. SPBP 18:1;(OH)2.
- Sphingoid base phosphates with known position of phosphate and of OH-positions is annotated by, e.g., SPBP[1] 18:1(4E);3OH.
Hierarchical shorthand notation for examples of sphingoid bases (sphingolipids with a free amino group)
Species level: Sum composition, Structure defined level: Molecular species with constituents and functional groups, Full structure level: Molecular species with constituents and functional groups including positions.
| Sphingoid base | Species level1 | Structure defined level | Full structure level |
|---|---|---|---|
| Sphingosine | SPB 18:1;O2 | SPB 18:1;(OH)2 |
SPB 18:1(4E);1OH,3OH
|
| 3-Keto-sphinganine | SPB 18:1;O2 | SPB 18:0;OH;oxo | SPB 18:0;1OH;3oxo |
| Sphinganine | SPB 18:0;O2 | SPB 18:0;(OH)2 | SPB 18:0;1OH,3OH |
| Sphingadiene | SPB 18:2;O2 | SPB 18:2;(OH)2 | SPB 18:2(4E,14Z);1OH,3OH |
| Phytosphingosine | SPB 18:0;O3 | SPB 18:0;(OH)3 | SPB 18:0;1OH,3OH,4OH |
| C20-Sphingosine | SPB 20:1;O2 | SPB 20:1;(OH)2 | SPB 20:1(4E);1OH,3OH |
| Sphingosine-1-phosphate | SPBP 18:1;O2 | SPBP 18:1;OH |
SPBP[1] 18:1(4E);3OH
|
| Sphinganine-1-phosphate | SPBP 18:0;O2 | SPBP 18:0;OH | SPBP[1] 18:0;3OH |
| 1-Deoxymethyl-sphinganine | SPB 17:0;O | SPB 17:0;OH | SPB 17:0;2OH |
| 1-Deoxy-sphinganine | SPB 18:0;O | SPB 18:0;OH | SPB 18:0;3OH |
| Lysoinositolphosphorylceramides | LIPC 18:0;O3 | LIPC 18:0;(OH)2 |
LIPC[1] 18:0;3OH,4OH
|
| Lysosphingomyelin | LSM 18:1;O2 | LSM 18:1;OH | LSM[1] 18:1(4E);3OH |
1 Annotation based on exact mass measurements using a high-resolution mass spectrometer.