Microarray analysis of RAW 264.7 cells treated with Kdo2-lipid A (KLA) and compactin (full time course)

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Kdo2-Lipid A / compactin gene array data - treatment:control ratios

KEGG pathway: Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (mmu00563)

Legend:graph_icon: View data/graphs for replicates
Gene symbol    Time course plot Accession Description Treatment 30min 1hr 2hr 4hr 8hr 12hr 24hr
Dpm2
KLA  Compactin  Compactin+KLA
 NM_010073 dolichol-phosphate (beta-D) mannosyltransferase 2 (Dpm2), mRNA [NM_010073] KLA1.360 1.140 1.260 1.210 1.320 1.530 1.480
Compactin1.310 1.170 1.130 1.220 1.150 1.090 1.280
KLA/Compactin1.150 1.120 1.120 1.270 1.220 1.140 1.360
Gpaa1
KLA  Compactin  Compactin+KLA
 NM_010331 GPI anchor attachment protein 1 (Gpaa1), mRNA [NM_010331] KLA1.250 1.080 1.130 1.080 0.780 0.780 0.860
Compactin1.280 1.120 1.100 1.140 1.000 0.950 0.860
KLA/Compactin1.160 1.130 1.110 0.960 0.870 0.680 0.830
Gpld1
KLA  Compactin  Compactin+KLA
 NM_008156 glycosylphosphatidylinositol specific phospholipase D1 (Gpld1), mRNA [NM_008156] KLA1.010 0.940 1.030 0.970 0.990 1.000 0.950
Compactin1.040 1.020 0.970 0.980 1.000 1.040 0.970
KLA/Compactin0.970 0.970 1.010 0.990 0.930 0.950 0.990
Pgap1
KLA  Compactin  Compactin+KLA
 AK033485 adult male colon cDNA, RIKEN full-length enriched library, clone:9030223K07 product:unclassifiable, full insert sequence. [AK033485] KLA1.110 0.840 0.880 0.790 0.570 0.670 0.800
Compactin1.090 0.980 1.010 1.080 1.060 0.920 0.730
KLA/Compactin1.130 0.890 0.840 0.780 0.580 0.640 0.780
Pgap1
KLA  Compactin  Compactin+KLA
 AK051360 12 days embryo spinal ganglion cDNA, RIKEN full-length enriched library, clone:D130039I04 product:hypothetical protein, full insert sequence [AK051360] KLA0.900 0.940 1.060 0.950 1.030 0.980 0.990
Compactin1.040 1.060 0.960 0.950 1.070 1.020 0.910
KLA/Compactin0.930 1.100 1.030 0.910 1.000 1.010 1.050
Pgap1
KLA  Compactin  Compactin+KLA
 AK051360 12 days embryo spinal ganglion cDNA, RIKEN full-length enriched library, clone:D130039I04 product:hypothetical protein, full insert sequence [AK051360] KLA0.910 1.010 1.030 0.960 0.950 0.980 1.020
Compactin1.120 0.980 1.010 1.110 0.990 0.980 1.030
KLA/Compactin1.000 1.030 0.980 0.940 0.990 0.980 0.950
Piga
KLA  Compactin  Compactin+KLA
 NM_011081 phosphatidylinositol glycan anchor biosynthesis, class A (Piga), mRNA [NM_011081] KLA1.000 1.120 0.920 0.850 1.010 1.060 1.600
Compactin0.910 0.980 1.120 0.960 0.910 0.920 0.940
KLA/Compactin1.050 1.110 0.960 1.090 1.060 1.250 1.690
Piga
KLA  Compactin  Compactin+KLA
 NM_011081 phosphatidylinositol glycan anchor biosynthesis, class A (Piga), mRNA [NM_011081] KLA1.050 1.530 1.160 0.980 1.580 1.650 2.350
Compactin0.960 1.080 0.950 0.820 0.990 1.320 1.250
KLA/Compactin0.830 1.330 1.340 1.230 1.240 1.650 2.630
Pigb
KLA  Compactin  Compactin+KLA
 NM_018889 phosphatidylinositol glycan anchor biosynthesis, class B (Pigb), mRNA [NM_018889] KLA0.920 1.030 0.980 0.920 0.940 1.090 0.970
Compactin0.980 1.000 1.030 1.030 0.930 1.010 1.010
KLA/Compactin1.050 0.970 0.950 0.940 0.960 0.960 1.010
Pigb
KLA  Compactin  Compactin+KLA
 NM_018889 phosphatidylinositol glycan anchor biosynthesis, class B (Pigb), mRNA [NM_018889] KLA0.930 1.010 1.080 0.960 0.860 1.020 0.890
Compactin1.000 1.120 1.130 1.070 0.970 1.030 1.000
KLA/Compactin1.070 0.960 1.060 1.020 0.900 0.930 0.990
Pigc
KLA  Compactin  Compactin+KLA
 NM_026078 phosphatidylinositol glycan anchor biosynthesis, class C (Pigc), transcript variant 1, mRNA [NM_026078] KLA0.850 0.820 0.930 1.020 1.000 1.020 0.790
Compactin0.900 0.970 0.900 0.940 0.960 0.950 1.160
KLA/Compactin0.810 0.800 0.930 0.860 1.380 1.190 0.620
Pigf
KLA  Compactin  Compactin+KLA
 NM_008838 phosphatidylinositol glycan anchor biosynthesis, class F (Pigf), mRNA [NM_008838] KLA1.080 1.010 1.090 1.120 0.800 0.880 1.660
Compactin0.930 1.100 1.010 0.990 1.000 1.060 1.170
KLA/Compactin0.990 1.110 1.020 1.010 0.810 1.130 1.650
Pigg
KLA  Compactin  Compactin+KLA
 124486986 phosphatidylinositol glycan anchor biosynthesis, class G KLA0.960 0.970 1.090 1.070 1.080 1.050 1.060
Compactin0.910 0.990 0.940 0.970 1.050 1.060 1.010
KLA/Compactin0.970 1.060 1.080 1.030 1.100 1.050 1.240
Pigg
KLA  Compactin  Compactin+KLA
 BC051059 phosphatidylinositol glycan anchor biosynthesis, class G, mRNA (cDNA clone IMAGE:5010465), containing frame-shift errors. [BC051059] KLA0.880 1.010 1.010 0.960 0.930 0.810 0.790
Compactin1.040 1.030 1.060 1.020 0.930 0.940 1.040
KLA/Compactin1.010 1.000 1.000 1.060 0.900 0.870 0.880
Pigg
KLA  Compactin  Compactin+KLA
 NM_001081234 phosphatidylinositol glycan anchor biosynthesis, class G (Pigg), mRNA [NM_001081234] KLA0.930 0.970 0.910 0.990 0.960 0.820 0.870
Compactin0.950 0.980 1.010 0.890 1.000 1.030 0.990
KLA/Compactin0.870 1.010 1.000 1.080 0.900 0.950 1.060
Pigh
KLA  Compactin  Compactin+KLA
 NM_029988 phosphatidylinositol glycan anchor biosynthesis, class H (Pigh), mRNA [NM_029988] KLA0.900 0.780 0.830 0.790 0.760 0.760 0.640
Compactin1.100 1.020 1.050 1.020 1.080 0.890 1.020
KLA/Compactin0.920 0.770 0.840 0.790 0.760 0.670 0.580
Pigh
KLA  Compactin  Compactin+KLA
 NM_029988 phosphatidylinositol glycan anchor biosynthesis, class H (Pigh), mRNA [NM_029988] KLA0.910 0.960 0.960 0.930 0.850 0.920 0.880
Compactin0.990 1.090 0.990 1.060 0.910 0.950 1.050
KLA/Compactin0.970 0.920 0.940 0.950 0.870 0.880 0.940
Pigk
KLA  Compactin  Compactin+KLA
 NM_178016 phosphatidylinositol glycan anchor biosynthesis, class K (Pigk), transcript variant 2, mRNA [NM_178016] KLA1.210 1.060 1.220 1.290 1.110 1.070 1.460
Compactin1.130 1.110 1.060 1.130 1.050 0.920 0.990
KLA/Compactin1.150 1.010 1.130 1.240 1.300 1.000 1.460
Pigl
KLA  Compactin  Compactin+KLA
 NM_001039536 phosphatidylinositol glycan anchor biosynthesis, class L (Pigl), mRNA [NM_001039536] KLA0.920 1.070 0.900 1.160 1.250 1.410 1.650
Compactin1.010 0.970 0.970 0.960 0.990 1.080 1.040
KLA/Compactin0.890 0.970 1.010 1.160 1.170 1.450 1.850
Pigm
KLA  Compactin  Compactin+KLA
 NM_026234 phosphatidylinositol glycan anchor biosynthesis, class M (Pigm), mRNA [NM_026234] KLA0.940 1.070 1.400 0.950 1.040 1.000 0.960
Compactin1.040 0.990 1.000 1.030 1.050 1.030 1.060
KLA/Compactin1.040 1.020 0.950 1.010 1.010 1.070 1.010
Pigm
KLA  Compactin  Compactin+KLA
 NM_026234 phosphatidylinositol glycan anchor biosynthesis, class M (Pigm), mRNA [NM_026234] KLA1.030 1.180 1.300 1.290 1.230 1.260 1.100
Compactin1.030 0.990 1.000 0.980 0.910 1.060 1.070
KLA/Compactin1.010 1.210 1.310 1.210 1.190 1.290 1.210
Pign
KLA  Compactin  Compactin+KLA
 AK082387 0 day neonate cerebellum cDNA, RIKEN full-length enriched library, clone:C230045A22 product:phosphatidylinositol glycan, class N, full insert sequence. [AK082387] KLA1.010 0.990 1.010 0.990 0.970 0.970 1.040
Compactin1.000 0.990 0.890 0.890 0.980 1.050 0.940
KLA/Compactin0.960 1.020 0.930 1.060 1.010 1.010 0.990
Pign
KLA  Compactin  Compactin+KLA
 NM_013784 phosphatidylinositol glycan anchor biosynthesis, class N (Pign), mRNA [NM_013784] KLA0.980 1.020 1.020 1.100 1.210 1.250 1.590
Compactin1.000 0.950 1.010 0.950 0.910 0.950 0.940
KLA/Compactin0.990 1.080 1.070 1.050 1.210 1.440 1.750
Pign
KLA  Compactin  Compactin+KLA
 NM_013784 phosphatidylinositol glycan anchor biosynthesis, class N (Pign), mRNA [NM_013784] KLA1.310 1.300 1.110 1.630 1.740 1.790 2.880
Compactin1.200 1.140 1.060 1.210 1.070 0.900 1.040
KLA/Compactin1.280 1.150 1.220 1.520 1.970 2.150 3.070
Pigo
KLA  Compactin  Compactin+KLA
 NM_020035 phosphatidylinositol glycan anchor biosynthesis, class O (Pigo), mRNA [NM_020035] KLA0.940 0.980 1.010 1.010 0.950 1.050 1.340
Compactin0.890 1.030 0.980 1.000 1.050 1.130 1.290
KLA/Compactin1.040 1.090 1.050 1.000 0.880 1.000 1.340
Pigp
KLA  Compactin  Compactin+KLA
 NM_019543 phosphatidylinositol glycan anchor biosynthesis, class P (Pigp), mRNA [NM_019543] KLA1.110 1.010 0.970 1.040 0.940 1.000 1.030
Compactin1.050 1.110 1.130 1.130 1.150 0.940 1.100
KLA/Compactin1.040 0.860 1.040 1.230 0.980 0.990 1.080
Pigq
KLA  Compactin  Compactin+KLA
 118130030 phosphatidylinositol glycan anchor biosynthesis, class Q KLA1.100 0.950 1.070 0.780 0.820 0.860 0.840
Compactin1.160 1.080 1.150 1.120 1.230 1.220 1.100
KLA/Compactin1.110 1.050 1.000 0.980 0.800 0.740 0.830
Pigq
KLA  Compactin  Compactin+KLA
 NM_011822 phosphatidylinositol glycan anchor biosynthesis, class Q (Pigq), mRNA [NM_011822] KLA1.140 1.040 1.140 0.960 0.940 0.890 0.800
Compactin1.040 1.170 1.170 1.140 1.250 1.090 1.170
KLA/Compactin1.100 1.000 1.040 1.000 0.950 0.800 0.860
Pigs
KLA  Compactin  Compactin+KLA
 NM_201406 phosphatidylinositol glycan anchor biosynthesis, class S (Pigs), mRNA [NM_201406] KLA0.940 1.010 0.920 0.800 0.880 0.890 1.230
Compactin0.880 0.960 0.850 0.850 1.000 1.070 0.980
KLA/Compactin0.860 1.030 0.810 0.830 0.770 1.000 1.730
Pigs
KLA  Compactin  Compactin+KLA
 NM_201406 phosphatidylinositol glycan anchor biosynthesis, class S (Pigs), mRNA [NM_201406] KLA0.990 1.050 1.080 0.950 0.790 0.980 1.330
Compactin1.030 1.130 1.150 1.070 0.950 0.990 1.090
KLA/Compactin1.060 1.010 1.100 1.010 0.840 0.990 1.350
Pigt
KLA  Compactin  Compactin+KLA
 NM_133779 phosphatidylinositol glycan anchor biosynthesis, class T (Pigt), mRNA [NM_133779] KLA0.990 1.010 1.000 1.000 0.950 0.880 1.030
Compactin0.990 0.920 1.010 1.050 1.320 0.980 0.920
KLA/Compactin0.940 0.980 1.050 0.900 0.970 0.870 0.960
Pigu
KLA  Compactin  Compactin+KLA
 NM_001004721 phosphatidylinositol glycan anchor biosynthesis, class U (Pigu), mRNA [NM_001004721] KLA0.880 1.040 0.910 1.170 1.050 0.940 1.050
Compactin0.890 1.020 1.010 1.010 1.010 1.130 0.940
KLA/Compactin1.000 0.950 1.050 1.070 0.920 0.930 1.330
Pigu
KLA  Compactin  Compactin+KLA
 NM_001004721 phosphatidylinositol glycan anchor biosynthesis, class U (Pigu), mRNA [NM_001004721] KLA0.940 0.960 0.980 0.860 0.890 0.970 1.190
Compactin0.950 0.950 0.940 0.840 0.910 0.940 1.080
KLA/Compactin0.990 0.950 0.980 0.990 0.790 0.880 1.170
Pigv
KLA  Compactin  Compactin+KLA
 142350613 phosphatidylinositol glycan anchor biosynthesis, class V KLA1.040 1.060 1.010 1.030 1.000 1.030 0.940
Compactin1.040 1.060 1.000 0.990 1.060 1.020 0.980
KLA/Compactin0.990 1.050 1.020 1.050 1.010 1.040 1.040
Pigv
KLA  Compactin  Compactin+KLA
 NM_178698 phosphatidylinositol glycan anchor biosynthesis, class V (Pigv), mRNA [NM_178698] KLA0.940 1.050 1.070 1.060 1.020 0.970 1.020
Compactin1.060 1.020 0.990 1.020 1.040 0.950 1.060
KLA/Compactin1.030 1.050 1.050 1.060 1.010 1.090 1.050
Pigw
KLA  Compactin  Compactin+KLA
 NM_027388 phosphatidylinositol glycan anchor biosynthesis, class W (Pigw), transcript variant 1, mRNA [NM_027388] KLA0.980 1.080 1.080 1.040 0.880 0.820 0.650
Compactin0.980 1.010 1.040 0.990 0.930 1.110 1.140
KLA/Compactin1.020 0.950 1.110 1.170 0.840 0.760 0.650
Pigw
KLA  Compactin  Compactin+KLA
 NM_027388 phosphatidylinositol glycan anchor biosynthesis, class W (Pigw), transcript variant 1, mRNA [NM_027388] KLA1.080 1.050 1.090 1.130 0.890 0.910 0.830
Compactin1.160 1.010 1.030 1.010 1.070 0.960 1.010
KLA/Compactin1.190 1.090 1.060 1.130 0.990 0.840 0.720
Pigx
KLA  Compactin  Compactin+KLA
 NM_024464 phosphatidylinositol glycan anchor biosynthesis, class X (Pigx), transcript variant 1, mRNA [NM_024464] KLA0.820 0.950 0.930 1.080 0.950 1.090 1.500
Compactin0.820 0.910 0.920 0.940 0.900 1.150 1.220
KLA/Compactin0.810 0.940 1.000 1.170 1.040 1.280 1.820
Pigx
KLA  Compactin  Compactin+KLA
 NM_024464 phosphatidylinositol glycan anchor biosynthesis, class X (Pigx), transcript variant 1, mRNA [NM_024464] KLA1.050 1.040 1.110 1.190 1.180 1.190 1.580
Compactin1.150 1.120 1.160 1.110 1.070 1.070 1.330
KLA/Compactin1.050 0.990 1.040 1.280 1.250 1.220 1.740
Pigz
KLA  Compactin  Compactin+KLA
 NM_172822 phosphatidylinositol glycan anchor biosynthesis, class Z (Pigz), mRNA [NM_172822] KLA1.010 0.990 0.880 0.810 0.760 0.970 0.720
Compactin1.060 1.030 1.020 1.020 0.970 0.900 1.030
KLA/Compactin1.020 0.920 0.980 0.760 0.900 0.920 0.840