Microarray analysis of RAW 264.7 cells treated with Kdo2-lipid A (KLA) and compactin (full time course)

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Kdo2-Lipid A / compactin gene array data - treatment:control ratios

KEGG pathway: Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate (mmu00532)

Legend:graph_icon: View data/graphs for replicates
Gene symbol    Time course plot Accession Description Treatment 30min 1hr 2hr 4hr 8hr 12hr 24hr
2010209O
12Rik
KLA  Compactin  Compactin+KLA
 NM_133913 RIKEN cDNA 2010209O12 gene (2010209O12Rik), mRNA [NM_133913] KLA0.990 0.880 0.990 0.810 1.290 1.780 0.880
Compactin1.040 1.020 0.960 1.050 0.970 1.050 1.000
KLA/Compactin0.940 0.920 0.860 0.800 1.300 2.050 0.760
2010209O
12Rik
KLA  Compactin  Compactin+KLA
 NM_133913 RIKEN cDNA 2010209O12 gene (2010209O12Rik), mRNA [NM_133913] KLA1.080 0.990 1.000 0.840 1.220 1.270 0.800
Compactin1.130 0.990 1.010 1.030 0.900 0.880 0.880
KLA/Compactin1.140 0.980 0.980 0.970 1.270 1.170 0.900
4631426J
05Rik
KLA  Compactin  Compactin+KLA
 158508649 RIKEN cDNA 4631426J05 gene KLA1.120 0.980 1.000 1.120 1.020 0.980 1.000
Compactin1.020 0.990 1.040 1.030 1.020 0.990 0.920
KLA/Compactin0.970 1.050 1.050 1.060 0.980 1.110 1.040
4631426J
05Rik
KLA  Compactin  Compactin+KLA
 NM_029935 RIKEN cDNA 4631426J05 gene (4631426J05Rik), mRNA [NM_029935] KLA1.010 1.070 1.020 1.080 1.040 1.010 1.060
Compactin0.980 0.990 0.980 1.000 1.090 1.030 1.020
KLA/Compactin1.020 1.050 1.000 1.010 1.050 1.060 1.010
B3galt6
KLA  Compactin  Compactin+KLA
 NM_080445 UDP-Gal:betaGal beta 1,3-galactosyltransferase, polypeptide 6 (B3galt6), mRNA [NM_080445] KLA1.030 1.010 0.930 0.980 0.770 0.720 0.610
Compactin1.110 1.140 1.170 1.220 1.060 1.190 1.140
KLA/Compactin1.060 0.940 0.900 1.020 0.720 0.810 0.590
B3gat3
KLA  Compactin  Compactin+KLA
 AK079723 0 day neonate thymus cDNA, RIKEN full-length enriched library, clone:A430034G17 product:beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I), full insert sequence [AK079723] KLA0.650 0.810 0.710 0.590 1.100 1.120 0.910
Compactin0.870 0.910 0.970 0.750 1.050 1.170 1.190
KLA/Compactin0.580 0.630 0.660 0.720 0.910 0.920 0.950
B3gat3
KLA  Compactin  Compactin+KLA
 NM_024256 beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I) (B3gat3), mRNA [NM_024256] KLA0.790 1.020 0.760 0.810 1.390 1.230 1.810
Compactin0.930 0.900 0.840 0.790 0.970 1.110 1.070
KLA/Compactin0.860 0.920 0.750 0.860 0.980 1.390 2.320
B3gat3
KLA  Compactin  Compactin+KLA
 NM_024256 beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I) (B3gat3), mRNA [NM_024256] KLA0.860 0.940 0.720 0.820 1.200 1.280 1.570
Compactin0.870 0.850 0.870 0.760 0.910 1.080 1.080
KLA/Compactin0.930 0.900 0.850 0.760 1.000 1.380 2.110
B3gat3
KLA  Compactin  Compactin+KLA
 NM_024256 beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I) (B3gat3), mRNA [NM_024256] KLA0.910 0.930 0.960 0.870 1.160 1.410 1.770
Compactin1.000 0.980 0.890 0.950 0.990 1.070 1.100
KLA/Compactin0.950 0.950 0.860 0.840 1.200 1.520 2.100
B4galt7
KLA  Compactin  Compactin+KLA
 NM_146045 xylosylprotein beta1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I) (B4galt7), mRNA [NM_146045] KLA0.860 0.850 0.760 0.740 0.930 1.110 1.260
Compactin1.100 1.030 0.990 1.170 1.210 1.290 1.350
KLA/Compactin1.040 0.780 0.900 0.820 1.080 1.280 1.170
Chpf
KLA  Compactin  Compactin+KLA
 48525358 chondroitin polymerizing factor KLA1.260 1.220 1.120 1.330 1.580 2.150 2.570
Compactin1.210 1.270 1.100 1.120 0.970 1.100 1.600
KLA/Compactin1.200 1.160 1.260 1.430 1.620 2.040 2.200
Chpf
KLA  Compactin  Compactin+KLA
 NM_001001566 chondroitin polymerizing factor (Chpf), transcript variant 1, mRNA [NM_001001566] KLA0.930 1.090 1.090 1.170 1.490 1.790 2.200
Compactin0.960 0.930 1.020 0.920 0.950 1.170 1.330
KLA/Compactin1.000 1.060 1.080 1.260 1.350 1.840 1.940
Chst11
KLA  Compactin  Compactin+KLA
 NM_021439 carbohydrate sulfotransferase 11 (Chst11), mRNA [NM_021439] KLA0.910 0.980 1.060 1.240 1.230 1.230 1.320
Compactin0.950 0.960 1.020 0.970 0.940 0.920 1.030
KLA/Compactin1.010 1.040 1.060 1.200 1.110 1.240 1.250
Chst11
KLA  Compactin  Compactin+KLA
 NM_021439 carbohydrate sulfotransferase 11 (Chst11), mRNA [NM_021439] KLA0.930 1.030 1.030 1.240 1.330 1.250 1.350
Compactin1.080 1.020 1.020 0.950 0.840 0.870 1.050
KLA/Compactin0.930 1.040 1.030 1.170 1.120 1.250 1.410
Chst11
KLA  Compactin  Compactin+KLA
 NM_021439 carbohydrate sulfotransferase 11 (Chst11), mRNA [NM_021439] KLA0.950 1.020 1.080 1.230 1.240 1.120 1.200
Compactin0.950 0.890 1.030 1.000 0.960 1.080 1.030
KLA/Compactin0.910 1.090 1.130 1.110 1.170 1.230 1.210
Chst12
KLA  Compactin  Compactin+KLA
 NM_021528 carbohydrate sulfotransferase 12 (Chst12), mRNA [NM_021528] KLA0.840 0.670 1.770 0.310 0.770 0.630 0.730
Compactin1.140 1.000 0.820 0.810 1.270 1.230 1.020
KLA/Compactin0.850 0.860 0.420 0.290 0.700 1.070 0.990
Chst12
KLA  Compactin  Compactin+KLA
 NM_021528 carbohydrate sulfotransferase 12 (Chst12), mRNA [NM_021528] KLA0.870 0.930 0.570 0.450 0.910 0.850 1.010
Compactin0.910 0.980 1.020 0.940 1.060 1.130 1.260
KLA/Compactin0.950 0.950 0.620 0.530 0.850 1.010 1.140
Chst13
KLA  Compactin  Compactin+KLA
 XM_978459 gb|PREDICTED: Mus musculus carbohydrate (chondroitin 4) sulfotransferase 13 (Chst13), mRNA [XM_978459] KLA1.000 0.980 1.020 0.920 1.000 0.940 1.050
Compactin1.090 0.970 1.020 1.080 1.070 1.020 1.000
KLA/Compactin1.010 1.050 1.010 0.940 0.950 0.950 0.960
Chst14
KLA  Compactin  Compactin+KLA
 NM_028117 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 (Chst14), mRNA [NM_028117] KLA1.140 0.860 0.690 0.720 1.280 1.210 0.720
Compactin1.120 1.080 1.140 1.230 1.090 0.860 1.010
KLA/Compactin1.150 0.820 0.640 0.820 1.260 1.120 0.610
Chst3
KLA  Compactin  Compactin+KLA
 NM_016803 carbohydrate (chondroitin 6/keratan) sulfotransferase 3 (Chst3), mRNA [NM_016803] KLA1.070 1.030 1.060 0.960 1.000 1.040 0.980
Compactin0.970 0.960 0.970 1.010 0.980 0.970 0.970
KLA/Compactin0.980 0.970 1.070 1.000 1.000 0.960 1.000
Chst3
KLA  Compactin  Compactin+KLA
 NM_016803 carbohydrate (chondroitin 6/keratan) sulfotransferase 3 (Chst3), mRNA [NM_016803] KLA1.160 0.830 1.420 0.500 0.300 0.370 0.470
Compactin1.190 1.230 1.090 1.140 1.140 1.300 1.460
KLA/Compactin1.140 0.930 1.460 0.530 0.350 0.410 0.450
Chst7
KLA  Compactin  Compactin+KLA
 NM_021715 carbohydrate (N-acetylglucosamino) sulfotransferase 7 (Chst7), mRNA [NM_021715] KLA1.010 1.100 0.910 0.980 1.090 1.200 1.230
Compactin1.100 0.950 1.050 1.100 0.980 0.860 0.900
KLA/Compactin1.020 1.040 0.920 1.130 1.190 1.220 1.440
Chsy1
KLA  Compactin  Compactin+KLA
 NM_001081163 carbohydrate (chondroitin) synthase 1 (Chsy1), mRNA [NM_001081163] KLA1.090 1.070 1.020 0.980 1.100 0.970 1.170
Compactin1.110 1.120 1.180 1.080 1.020 1.200 1.240
KLA/Compactin1.150 1.090 1.040 1.080 1.050 1.060 1.240
Chsy3
KLA  Compactin  Compactin+KLA
 AK043732 10 days neonate cortex cDNA, RIKEN full-length enriched library, clone:A830026G02 product:hypothetical protein, full insert sequence. [AK043732] KLA1.000 0.950 0.980 0.980 0.990 1.020 1.050
Compactin0.990 0.990 0.980 1.010 1.000 1.010 1.020
KLA/Compactin0.990 1.000 0.990 0.940 1.010 0.950 0.960
Chsy3
KLA  Compactin  Compactin+KLA
 NM_001081328 chondroitin sulfate synthase 3 (Chsy3), mRNA [NM_001081328] KLA1.040 0.980 0.970 0.980 0.950 1.090 0.960
Compactin0.940 0.970 1.000 1.050 0.890 1.020 1.130
KLA/Compactin0.960 1.000 0.980 1.080 1.090 0.980 1.020
Chsy3
KLA  Compactin  Compactin+KLA
 NM_001081328 chondroitin sulfate synthase 3 (Chsy3), mRNA [NM_001081328] KLA1.100 0.980 0.990 1.030 1.100 1.080 1.000
Compactin0.970 0.940 1.000 1.000 0.970 1.080 0.960
KLA/Compactin0.970 1.020 0.970 0.980 1.010 0.960 0.940
Csgalnac
t1
KLA  Compactin  Compactin+KLA
 NM_172753 chondroitin sulfate N-acetylgalactosaminyltransferase 1 (Csgalnact1), mRNA [NM_172753] KLA1.010 0.980 1.030 0.970 1.000 0.960 0.970
Compactin1.000 0.980 1.050 0.980 0.950 1.000 0.960
KLA/Compactin0.960 1.050 0.960 0.960 1.020 1.020 1.020
Csgalnac
t2
KLA  Compactin  Compactin+KLA
 NM_030165 chondroitin sulfate N-acetylgalactosaminyltransferase 2 (Csgalnact2), mRNA [NM_030165] KLA1.040 1.050 0.890 0.840 0.590 0.610 0.490
Compactin1.060 1.120 1.000 1.170 0.960 0.980 1.070
KLA/Compactin1.110 0.990 0.810 0.820 0.620 0.630 0.440
Dse
KLA  Compactin  Compactin+KLA
 NM_172508 dermatan sulfate epimerase (Dse), mRNA [NM_172508] KLA0.990 0.980 0.960 1.020 1.170 1.120 0.710
Compactin1.030 0.970 1.000 1.100 0.910 0.930 0.870
KLA/Compactin1.030 0.930 1.000 1.070 1.190 1.080 0.660
Ust
KLA  Compactin  Compactin+KLA
 NM_177387 uronyl-2-sulfotransferase (Ust), mRNA [NM_177387] KLA0.980 0.980 1.030 0.980 1.040 0.940 0.980
Compactin1.030 1.040 1.000 0.930 1.070 1.010 1.030
KLA/Compactin0.960 1.020 0.990 1.000 1.040 1.030 0.980
Ust
KLA  Compactin  Compactin+KLA
 NM_177387 uronyl-2-sulfotransferase (Ust), mRNA [NM_177387] KLA0.990 1.020 1.090 1.050 1.070 1.120 1.000
Compactin1.050 1.050 0.940 1.000 0.980 0.980 1.010
KLA/Compactin0.960 0.960 1.090 1.000 1.000 1.000 1.070
Xylt1
KLA  Compactin  Compactin+KLA
 120407063 xylosyltransferase 1 KLA0.970 0.990 1.000 0.930 1.140 1.320 1.390
Compactin0.950 1.010 0.920 0.980 0.980 1.060 1.130
KLA/Compactin1.090 0.980 0.940 0.890 1.150 1.220 1.200
Xylt1
KLA  Compactin  Compactin+KLA
 AJ539164 mRNA for xylosyltransferase I (Xylt1 gene) [AJ539164] KLA0.980 1.060 1.030 1.120 1.120 1.000 1.180
Compactin1.010 1.070 0.950 1.050 1.070 1.080 0.990
KLA/Compactin0.970 1.000 1.000 1.120 1.120 1.080 1.130
Xylt2
KLA  Compactin  Compactin+KLA
 NM_145828 xylosyltransferase II (Xylt2), mRNA [NM_145828] KLA0.890 0.800 2.020 3.340 2.350 3.390 3.820
Compactin0.980 0.860 0.930 1.040 0.890 1.000 1.200
KLA/Compactin1.000 0.780 1.940 3.870 4.150 4.520 4.950
Xylt2
KLA  Compactin  Compactin+KLA
 NM_145828 xylosyltransferase II (Xylt2), mRNA [NM_145828] KLA1.160 0.810 2.020 3.500 3.160 4.670 4.230
Compactin1.010 0.990 1.090 1.090 1.040 1.090 1.260
KLA/Compactin1.130 0.800 2.560 4.190 3.910 5.860 5.230