Microarray analysis of RAW 264.7 cells treated with Kdo2-lipid A (KLA) and compactin (full time course)

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Kdo2-Lipid A / compactin gene array data - treatment:control ratios

KEGG pathway: Mucin type O-Glycan biosynthesis (mmu00512)

Legend:graph_icon: View data/graphs for replicates
Gene symbol    Time course plot Accession Description Treatment 30min 1hr 2hr 4hr 8hr 12hr 24hr
4930431L
04Rik
KLA  Compactin  Compactin+KLA
 NM_175032 RIKEN cDNA 4930431L04 gene (4930431L04Rik), mRNA [NM_175032] KLA1.020 0.980 0.970 1.140 0.960 0.960 0.970
Compactin1.100 0.980 1.000 0.990 0.990 0.970 0.970
KLA/Compactin1.040 1.030 1.010 1.010 0.970 1.060 0.980
B4galt5
KLA  Compactin  Compactin+KLA
 NM_019835 UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5 (B4galt5), mRNA [NM_019835] KLA0.990 1.130 1.080 1.230 1.490 1.150 0.970
Compactin1.000 1.080 1.010 0.960 1.010 1.080 0.990
KLA/Compactin1.080 1.140 1.160 1.210 1.320 1.190 1.100
C1galt1
KLA  Compactin  Compactin+KLA
 AK008884 adult male stomach cDNA, RIKEN full-length enriched library, clone:2210410E06 product:hypothetical protein, full insert sequence. [AK008884] KLA0.900 1.000 0.810 0.980 1.080 0.930 0.810
Compactin0.980 0.870 1.020 0.840 1.010 1.290 1.390
KLA/Compactin0.950 1.030 1.020 0.810 0.750 1.220 1.220
C1galt1
KLA  Compactin  Compactin+KLA
 NM_052993 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1 (C1galt1), mRNA [NM_052993] KLA0.910 1.130 1.280 1.160 1.490 2.050 2.590
Compactin1.010 0.980 0.960 0.960 0.880 1.030 1.170
KLA/Compactin0.920 1.140 1.230 1.200 1.550 2.530 2.540
C1galt1c
1
KLA  Compactin  Compactin+KLA
 AK161729 adult male thymus cDNA, RIKEN full-length enriched library, clone:5830428K17 product:hypothetical protein, full insert sequence. [AK161729] KLA1.070 1.040 1.070 1.000 1.040 0.960 0.950
Compactin0.960 1.010 0.940 1.000 1.040 1.060 1.010
KLA/Compactin0.980 1.050 1.060 0.950 1.000 0.940 1.010
C1galt1c
1
KLA  Compactin  Compactin+KLA
 NM_021550 C1GALT1-specific chaperone 1 (C1galt1c1), mRNA [NM_021550] KLA0.920 0.940 0.980 1.120 0.900 1.060 0.610
Compactin0.870 1.000 0.870 0.870 0.980 1.000 1.160
KLA/Compactin0.890 1.120 0.970 1.000 1.170 0.920 0.470
Galnt1
KLA  Compactin  Compactin+KLA
 NM_013814 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (Galnt1), mRNA [NM_013814] KLA0.830 1.050 0.830 0.870 0.750 0.810 0.810
Compactin0.970 1.010 0.940 0.940 0.980 1.100 1.050
KLA/Compactin0.950 1.040 0.940 0.800 0.680 0.830 1.160
Galnt10
KLA  Compactin  Compactin+KLA
 BC016585 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10, mRNA (cDNA clone MGC:27969 IMAGE:3595220), complete cds. [BC016585] KLA0.970 0.960 0.850 0.740 0.570 0.670 0.590
Compactin1.070 1.010 0.980 0.980 1.010 1.000 0.990
KLA/Compactin1.000 1.050 0.910 0.630 0.630 0.560 0.600
Galnt10
KLA  Compactin  Compactin+KLA
 NM_134189 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (Galnt10), mRNA [NM_134189] KLA1.070 1.080 0.970 0.560 0.470 0.540 0.480
Compactin1.130 1.080 1.230 1.120 1.050 1.140 1.110
KLA/Compactin1.250 1.040 1.000 0.610 0.500 0.530 0.420
Galnt11
KLA  Compactin  Compactin+KLA
 AK079811 0 day neonate thymus cDNA, RIKEN full-length enriched library, clone:A430075I06 product:unclassifiable, full insert sequence. [AK079811] KLA1.040 0.970 0.990 1.040 0.920 1.000 0.980
Compactin1.040 0.980 1.090 0.950 1.040 0.960 0.940
KLA/Compactin0.930 1.000 0.980 1.020 0.940 0.980 0.970
Galnt11
KLA  Compactin  Compactin+KLA
 NM_144908 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (Galnt11), mRNA [NM_144908] KLA1.180 1.140 1.060 0.930 0.490 0.730 1.060
Compactin1.240 1.240 1.030 1.110 0.990 1.100 0.980
KLA/Compactin1.200 1.160 1.120 1.060 0.520 0.760 0.910
Galnt12
KLA  Compactin  Compactin+KLA
 NM_172693 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12 (Galnt12), mRNA [NM_172693] KLA1.060 1.200 1.020 1.000 0.980 0.970 0.940
Compactin1.060 0.990 1.040 1.020 1.000 0.980 0.960
KLA/Compactin1.050 1.010 1.040 1.010 0.980 1.000 1.010
Galnt13
KLA  Compactin  Compactin+KLA
 AK035964 16 days neonate cerebellum cDNA, RIKEN full-length enriched library, clone:9630021K14 product:unclassifiable, full insert sequence [AK035964] KLA1.040 1.040 1.070 1.110 1.050 0.990 0.930
Compactin0.970 1.000 1.000 0.990 1.090 1.040 1.030
KLA/Compactin1.050 1.010 1.080 1.070 1.020 1.040 0.950
Galnt13
KLA  Compactin  Compactin+KLA
 AK035964 16 days neonate cerebellum cDNA, RIKEN full-length enriched library, clone:9630021K14 product:unclassifiable, full insert sequence [AK035964] KLA1.060 0.970 0.970 1.000 0.960 1.070 1.030
Compactin1.050 0.970 1.010 0.990 1.050 1.090 1.030
KLA/Compactin0.960 1.010 1.040 0.980 0.990 1.050 0.890
Galnt13
KLA  Compactin  Compactin+KLA
 NM_173030 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (Galnt13), mRNA [NM_173030] KLA1.030 0.970 1.000 0.960 0.980 0.930 1.030
Compactin1.110 1.010 0.970 1.020 1.070 1.020 0.980
KLA/Compactin1.000 1.020 1.020 1.010 0.980 1.000 0.990
Galnt13
KLA  Compactin  Compactin+KLA
 NM_173030 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (Galnt13), mRNA [NM_173030] KLA1.030 1.020 0.970 1.020 1.040 1.080 0.940
Compactin0.970 0.960 1.000 0.980 1.030 1.010 0.980
KLA/Compactin0.960 0.980 0.960 0.980 1.070 0.900 0.990
Galnt14
KLA  Compactin  Compactin+KLA
 AK002747 adult male kidney cDNA, RIKEN full-length enriched library, clone:0610033M06 product:RIKEN cDNA 0610033M06 gene, full insert sequence. [AK002747] KLA0.990 1.000 1.020 0.900 1.020 0.960 0.970
Compactin0.990 0.940 0.970 0.980 1.070 1.000 0.960
KLA/Compactin1.000 1.010 0.980 1.020 1.000 1.030 0.950
Galnt14
KLA  Compactin  Compactin+KLA
 NM_027864 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (Galnt14), mRNA [NM_027864] KLA1.050 1.060 0.990 0.960 1.020 1.040 1.010
Compactin0.920 0.970 0.990 0.980 0.980 1.000 1.010
KLA/Compactin0.990 0.910 1.050 1.040 0.940 0.940 0.980
Galnt2
KLA  Compactin  Compactin+KLA
 NM_139272 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (Galnt2), mRNA [NM_139272] KLA0.930 0.890 0.880 0.830 0.650 0.730 1.000
Compactin0.910 0.930 0.880 0.750 1.050 0.870 1.050
KLA/Compactin0.930 0.970 0.860 0.810 0.690 0.890 1.440
Galnt2
KLA  Compactin  Compactin+KLA
 NM_139272 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (Galnt2), mRNA [NM_139272] KLA1.080 0.980 0.970 0.890 0.850 0.980 1.440
Compactin1.070 0.980 0.940 1.020 0.940 0.880 0.920
KLA/Compactin1.150 0.990 0.970 0.910 0.930 1.020 1.230
Galnt3
KLA  Compactin  Compactin+KLA
 AK087219 0 day neonate lung cDNA, RIKEN full-length enriched library, clone:E030036B02 product:UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3, full insert sequence. [AK087219] KLA0.990 1.060 0.970 1.030 1.080 1.070 1.010
Compactin1.030 0.990 0.990 1.060 1.120 1.080 1.130
KLA/Compactin1.030 1.000 0.960 1.070 1.040 1.230 1.020
Galnt3
KLA  Compactin  Compactin+KLA
 NM_015736 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (Galnt3), mRNA [NM_015736] KLA0.890 0.990 1.020 1.360 2.140 2.830 3.600
Compactin0.860 0.950 1.070 1.000 0.960 0.920 3.740
KLA/Compactin0.890 1.000 1.070 1.530 2.710 4.150 5.380
Galnt3
KLA  Compactin  Compactin+KLA
 U70538 UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-T3 mRNA, complete cds. [U70538] KLA0.950 0.960 1.000 1.320 1.990 2.750 3.420
Compactin0.920 0.990 1.010 0.950 0.970 0.950 3.630
KLA/Compactin0.850 0.890 1.090 1.490 2.090 4.040 5.080
Galnt4
KLA  Compactin  Compactin+KLA
 NM_015737 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (Galnt4), mRNA [NM_015737] KLA1.010 1.100 1.030 1.200 1.150 1.000 0.870
Compactin1.030 1.010 1.010 0.980 0.970 1.070 1.140
KLA/Compactin0.930 1.090 1.080 1.270 1.100 1.050 0.860
Galnt4
KLA  Compactin  Compactin+KLA
 NM_015737 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (Galnt4), mRNA [NM_015737] KLA1.040 1.170 1.150 1.340 1.130 0.870 0.610
Compactin1.160 1.000 1.030 1.090 0.980 1.090 1.480
KLA/Compactin1.190 1.120 1.240 1.370 1.220 0.810 0.510
Galnt6
KLA  Compactin  Compactin+KLA
 NM_172451 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (Galnt6), mRNA [NM_172451] KLA0.950 0.990 0.960 0.810 1.420 1.390 1.320
Compactin0.950 0.990 0.870 0.810 0.690 0.630 0.650
KLA/Compactin0.950 1.110 0.880 0.610 0.970 1.150 1.210
Galnt6
KLA  Compactin  Compactin+KLA
 NM_172451 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (Galnt6), mRNA [NM_172451] KLA0.970 1.010 1.070 0.810 1.320 1.280 1.620
Compactin1.020 0.920 0.950 1.060 0.710 0.740 0.720
KLA/Compactin1.120 1.050 1.010 0.790 0.870 1.090 1.380
Galnt7
KLA  Compactin  Compactin+KLA
 NM_144731 UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7 (Galnt7), mRNA [NM_144731] KLA1.060 0.970 0.990 1.010 0.820 0.970 0.810
Compactin0.940 1.020 0.910 0.980 0.850 1.030 1.060
KLA/Compactin1.080 1.020 0.940 1.020 0.860 1.150 0.820
Galnt7
KLA  Compactin  Compactin+KLA
 NM_144731 UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7 (Galnt7), mRNA [NM_144731] KLA1.280 0.930 1.040 0.890 1.110 1.220 0.960
Compactin1.040 1.120 1.060 1.000 0.970 0.930 0.990
KLA/Compactin1.150 0.930 1.150 1.120 1.030 1.100 1.000
Galntl1
KLA  Compactin  Compactin+KLA
 NM_001081421 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1 (Galntl1), mRNA [NM_001081421] KLA0.980 1.210 0.930 0.870 0.930 1.020 1.050
Compactin0.920 1.010 1.010 0.970 0.930 1.010 1.100
KLA/Compactin1.010 0.930 0.940 0.960 0.960 0.970 1.020
Galntl2
KLA  Compactin  Compactin+KLA
 153792802 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 2 KLA0.920 1.020 1.090 1.010 1.040 1.030 1.080
Compactin0.980 0.940 0.980 0.970 1.020 1.020 1.020
KLA/Compactin1.070 1.030 1.000 1.030 1.020 1.030 0.950
Galntl2
KLA  Compactin  Compactin+KLA
 AK019470 0 day neonate skin cDNA, RIKEN full-length enriched library, clone:4631401E18 product:similar to UDP-N-ACETYL-ALPHA-D-GALACTOSAMINE:POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 7 [Homo sapiens], full insert sequence [AK019470] KLA1.030 0.960 0.990 1.020 1.050 1.020 1.030
Compactin0.920 1.020 1.020 0.990 0.990 0.950 1.000
KLA/Compactin0.930 1.030 1.010 1.060 1.010 0.990 1.050
Galntl4
KLA  Compactin  Compactin+KLA
 AK084671 13 days embryo heart cDNA, RIKEN full-length enriched library, clone:D330027L06 product:hypothetical protein, full insert sequence. [AK084671] KLA1.000 1.010 0.950 1.070 1.030 1.000 0.980
Compactin1.050 1.020 0.900 1.070 0.970 0.980 1.030
KLA/Compactin1.020 1.020 1.000 1.100 1.030 0.960 0.990
Galntl4
KLA  Compactin  Compactin+KLA
 NM_173739 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 4 (Galntl4), mRNA [NM_173739] KLA1.040 0.900 1.050 0.970 0.980 1.040 1.050
Compactin1.000 0.990 1.000 1.060 0.990 0.990 0.970
KLA/Compactin1.030 1.150 0.970 1.010 1.040 0.990 0.980
Galntl5
KLA  Compactin  Compactin+KLA
 NM_026449 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 5 (Galntl5), mRNA [NM_026449] KLA0.980 1.000 0.970 1.060 0.990 0.950 0.960
Compactin1.050 1.030 1.010 1.040 0.980 1.000 1.000
KLA/Compactin1.000 1.040 1.010 0.980 0.980 1.070 0.970
Gcnt1
KLA  Compactin  Compactin+KLA
 NM_010265 glucosaminyl (N-acetyl) transferase 1, core 2 (Gcnt1), mRNA [NM_010265] KLA1.100 1.010 0.880 0.700 0.840 1.140 1.710
Compactin1.020 1.060 1.020 1.030 1.100 1.410 1.650
KLA/Compactin1.040 1.030 0.840 0.750 0.900 1.440 1.980
Gcnt1
KLA  Compactin  Compactin+KLA
 NM_173442 glucosaminyl (N-acetyl) transferase 1, core 2 (Gcnt1), mRNA [NM_173442] KLA0.960 0.810 0.710 0.650 0.790 0.990 1.220
Compactin1.050 0.950 0.900 0.950 1.170 1.200 1.630
KLA/Compactin0.990 0.820 0.660 0.670 0.930 1.290 1.170
Gcnt3
KLA  Compactin  Compactin+KLA
 NM_028087 glucosaminyl (N-acetyl) transferase 3, mucin type (Gcnt3), mRNA [NM_028087] KLA1.020 0.990 0.980 1.020 0.990 0.970 0.980
Compactin1.090 1.050 0.990 1.010 1.050 1.000 1.010
KLA/Compactin1.020 1.080 0.990 1.050 0.990 0.980 1.020
St3gal1
KLA  Compactin  Compactin+KLA
 NM_009177 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 (St3gal1), mRNA [NM_009177] KLA0.880 1.660 2.650 3.270 2.900 2.790 5.300
Compactin0.890 0.890 0.880 0.860 1.340 1.130 1.000
KLA/Compactin0.960 1.490 2.450 2.820 3.440 4.810 7.850
St3gal2
KLA  Compactin  Compactin+KLA
 NM_009179 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 (St3gal2), mRNA [NM_009179] KLA0.950 0.960 0.940 0.900 0.920 0.920 1.050
Compactin1.000 1.020 1.030 1.060 0.980 1.080 1.000
KLA/Compactin1.020 0.970 0.960 0.920 0.900 1.010 0.950
St3gal2
KLA  Compactin  Compactin+KLA
 NM_009179 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 (St3gal2), mRNA [NM_009179] KLA1.150 1.090 0.950 0.750 0.790 0.940 0.940
Compactin1.160 1.110 1.070 1.080 1.180 1.070 1.200
KLA/Compactin1.210 0.990 0.870 0.770 0.850 0.970 0.920
St6galna
c1
KLA  Compactin  Compactin+KLA
 NM_011371 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (St6galnac1), mRNA [NM_011371] KLA0.980 1.070 0.990 1.020 0.960 1.070 1.000
Compactin1.030 1.020 0.990 0.960 1.010 1.010 1.040
KLA/Compactin0.970 0.980 1.030 0.980 0.980 1.000 1.030
Wbscr17
KLA  Compactin  Compactin+KLA
 NM_145218 Williams-Beuren syndrome chromosome region 17 homolog (human) (Wbscr17), mRNA [NM_145218] KLA0.940 0.980 1.030 1.040 1.040 1.030 1.030
Compactin0.970 1.010 1.000 1.020 1.090 1.020 0.980
KLA/Compactin0.970 0.950 1.000 0.940 1.040 0.950 0.930
Wbscr17
KLA  Compactin  Compactin+KLA
 NM_145218 Williams-Beuren syndrome chromosome region 17 homolog (human) (Wbscr17), mRNA [NM_145218] KLA0.970 0.990 1.030 0.910 1.010 1.070 0.950
Compactin0.960 1.000 0.960 0.990 0.990 0.980 1.020
KLA/Compactin1.030 1.060 1.020 1.020 1.030 1.000 0.910