Microarray analysis of RAW 264.7 cells treated with Kdo2-lipid A (KLA) and compactin (full time course)

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Kdo2-Lipid A / compactin gene array data - treatment:control ratios

KEGG pathway: D-Glutamine and D-glutamate metabolism (mmu00471)

Legend:graph_icon: View data/graphs for replicates
Gene symbol    Time course plot Accession Description Treatment 30min 1hr 2hr 4hr 8hr 12hr 24hr
Gls
KLA  Compactin  Compactin+KLA
164607131 glutaminase KLA0.920 0.900 0.780 0.580 0.610 0.700 0.370
Compactin0.830 0.890 0.830 0.930 0.950 1.020 1.120
KLA/Compactin0.840 0.930 0.800 0.460 0.690 0.520 0.300
Gls
KLA  Compactin  Compactin+KLA
NM_001081081 glutaminase (Gls), nuclear gene encoding mitochondrial protein, transcript variant 1, mRNA [NM_001081081] KLA0.910 1.010 1.070 0.990 1.130 1.100 0.820
Compactin0.990 1.000 1.030 1.000 1.020 1.080 1.020
KLA/Compactin1.010 1.050 0.990 0.850 1.110 1.080 0.850
Gls
KLA  Compactin  Compactin+KLA
NM_001113383 glutaminase (Gls), nuclear gene encoding mitochondrial protein, transcript variant 2, mRNA [NM_001113383] KLA0.920 1.170 1.430 1.410 0.890 0.720 0.550
Compactin0.880 0.910 0.970 0.880 0.930 1.000 0.980
KLA/Compactin0.830 1.040 1.260 1.460 0.980 0.590 0.480
Gls2
KLA  Compactin  Compactin+KLA
142348692 glutaminase 2 (liver, mitochondrial) KLA1.000 1.050 1.000 0.970 0.700 0.700 0.760
Compactin0.980 1.150 1.010 1.050 1.040 1.050 0.930
KLA/Compactin0.970 1.040 0.890 0.930 0.710 0.690 0.780
Gls2
KLA  Compactin  Compactin+KLA
NM_001033264 glutaminase 2 (liver, mitochondrial) (Gls2), nuclear gene encoding mitochondrial protein, mRNA [NM_001033264] KLA1.030 1.070 1.030 0.910 0.710 0.700 0.750
Compactin1.060 1.170 1.050 1.060 1.080 1.150 0.980
KLA/Compactin1.010 1.090 0.950 0.920 0.710 0.650 0.750
Glud1
KLA  Compactin  Compactin+KLA
NM_008133 glutamate dehydrogenase 1 (Glud1), mRNA [NM_008133] KLA1.230 1.100 1.150 0.870 0.830 0.720 0.640
Compactin1.110 1.150 1.270 1.190 1.390 1.190 1.310
KLA/Compactin1.210 0.920 1.040 0.850 0.910 0.860 0.580