Microarray analysis of RAW 264.7 cells treated with Kdo2-lipid A (KLA) and compactin (full time course)

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Kdo2-Lipid A / compactin gene array data - treatment:control ratios

KEGG pathway: Phenylalanine, tyrosine and tryptophan biosynthesis (mmu00400)

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Gene symbol    Time course plot Accession Description Treatment 30min 1hr 2hr 4hr 8hr 12hr 24hr
4930438A
08Rik
KLA  Compactin  Compactin+KLA
 XM_001477470 gb|PREDICTED: Mus musculus RIKEN cDNA 4930438A08 gene (4930438A08Rik), mRNA [XM_001477470] KLA0.910 0.990 0.990 1.000 1.560 4.520 10.370
Compactin0.960 1.000 1.030 0.970 0.930 0.960 1.050
KLA/Compactin0.960 0.990 1.010 1.090 1.630 5.840 12.850
Got1
KLA  Compactin  Compactin+KLA
 NM_010324 glutamate oxaloacetate transaminase 1, soluble (Got1), mRNA [NM_010324] KLA0.990 0.960 0.820 0.740 0.780 1.140 1.350
Compactin1.110 1.060 1.070 1.250 0.950 0.700 0.640
KLA/Compactin1.020 1.050 0.850 0.770 0.760 1.070 1.070
Got2
KLA  Compactin  Compactin+KLA
 NM_010325 glutamate oxaloacetate transaminase 2, mitochondrial (Got2), nuclear gene encoding mitochondrial protein, mRNA [NM_010325] KLA0.960 1.030 1.060 0.940 0.870 0.810 1.090
Compactin1.130 1.000 1.060 1.010 1.080 0.990 0.880
KLA/Compactin1.100 1.000 1.120 1.040 0.870 0.940 0.940
Il4i1
KLA  Compactin  Compactin+KLA
 NM_010215 interleukin 4 induced 1 (Il4i1), mRNA [NM_010215] KLA1.160 1.780 6.000 7.610 4.240 1.830 0.970
Compactin1.000 1.090 1.000 1.040 0.830 0.820 1.690
KLA/Compactin1.260 2.060 5.680 8.020 5.700 2.690 1.220
Lao1
KLA  Compactin  Compactin+KLA
 NM_133892 L-amino acid oxidase 1 (Lao1), mRNA [NM_133892] KLA1.040 0.950 0.920 1.020 0.930 1.010 0.920
Compactin1.030 0.990 1.130 1.010 1.060 1.010 0.960
KLA/Compactin0.970 0.930 0.980 1.050 0.970 1.030 0.970
Pah
KLA  Compactin  Compactin+KLA
 NM_008777 phenylalanine hydroxylase (Pah), mRNA [NM_008777] KLA0.960 0.980 1.050 0.990 0.990 1.060 1.000
Compactin0.970 1.020 0.980 1.020 1.070 0.980 0.910
KLA/Compactin1.050 0.980 1.050 0.970 1.040 0.990 0.950
Tat
KLA  Compactin  Compactin+KLA
 NM_146214 tyrosine aminotransferase (Tat), nuclear gene encoding mitochondrial protein, mRNA [NM_146214] KLA1.110 0.960 1.040 1.030 1.040 1.020 1.050
Compactin0.940 0.890 1.010 1.030 1.040 1.080 0.980
KLA/Compactin0.980 1.030 1.080 1.070 1.030 1.130 1.110