Microarray analysis of RAW 264.7 cells treated with Kdo2-lipid A (KLA) and compactin (full time course)

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Kdo2-Lipid A / compactin gene array data - treatment:control ratios

KEGG pathway: Ascorbate and aldarate metabolism (mmu00053)

Legend:graph_icon: View data/graphs for replicates
Gene symbol    Time course plot Accession Description Treatment 30min 1hr 2hr 4hr 8hr 12hr 24hr
Aldh1b1
KLA  Compactin  Compactin+KLA
 NM_028270 aldehyde dehydrogenase 1 family, member B1 (Aldh1b1), nuclear gene encoding mitochondrial protein, mRNA [NM_028270] KLA0.990 0.930 1.090 2.540 4.350 5.420 5.340
Compactin1.030 0.980 1.040 1.190 0.880 0.810 1.090
KLA/Compactin0.970 0.900 1.030 2.940 5.190 6.900 5.710
Aldh2
KLA  Compactin  Compactin+KLA
 AK163452 adult male corpora quadrigemina cDNA, RIKEN full-length enriched library, clone:B230105J09 product:aldehyde dehydrogenase 2, mitochondrial, full insert sequence [AK163452] KLA0.980 1.050 1.010 0.980 1.000 1.030 1.060
Compactin1.050 1.010 1.010 1.030 1.070 1.030 0.970
KLA/Compactin0.990 1.000 1.030 0.950 1.030 0.960 1.050
Aldh2
KLA  Compactin  Compactin+KLA
 NM_009656 aldehyde dehydrogenase 2, mitochondrial (Aldh2), nuclear gene encoding mitochondrial protein, mRNA [NM_009656] KLA0.940 0.930 0.960 0.980 0.830 0.900 0.880
Compactin1.080 0.910 0.930 1.150 1.580 1.000 0.840
KLA/Compactin1.050 1.030 1.050 0.790 1.020 0.880 0.860
Aldh3a2
KLA  Compactin  Compactin+KLA
 NM_007437 aldehyde dehydrogenase family 3, subfamily A2 (Aldh3a2), mRNA [NM_007437] KLA1.040 0.900 0.840 0.840 1.130 1.330 1.150
Compactin1.020 1.070 0.990 1.170 1.000 0.960 1.110
KLA/Compactin1.110 0.870 0.880 0.930 1.320 1.440 1.120
Aldh7a1
KLA  Compactin  Compactin+KLA
 NM_138600 aldehyde dehydrogenase family 7, member A1 (Aldh7a1), mRNA [NM_138600] KLA0.970 0.980 0.980 1.060 1.020 1.080 1.220
Compactin1.000 1.070 0.990 1.010 0.950 0.980 0.990
KLA/Compactin1.000 1.020 1.010 1.150 1.070 1.060 1.260
Aldh7a1
KLA  Compactin  Compactin+KLA
 NM_138600 aldehyde dehydrogenase family 7, member A1 (Aldh7a1), mRNA [NM_138600] KLA1.000 0.990 1.000 1.070 1.060 1.000 1.010
Compactin0.990 0.950 1.010 0.990 0.970 0.950 1.000
KLA/Compactin1.060 1.010 0.990 0.990 0.920 1.020 0.960
Aldh9a1
KLA  Compactin  Compactin+KLA
 NM_019993 aldehyde dehydrogenase 9, subfamily A1 (Aldh9a1), mRNA [NM_019993] KLA0.900 0.880 0.920 0.850 0.780 0.700 0.750
Compactin0.890 0.960 0.920 0.920 1.080 1.090 0.980
KLA/Compactin0.840 0.950 0.950 0.850 0.750 0.710 0.870
Aldh9a1
KLA  Compactin  Compactin+KLA
 NM_019993 aldehyde dehydrogenase 9, subfamily A1 (Aldh9a1), mRNA [NM_019993] KLA0.930 0.840 0.770 0.830 0.740 0.590 0.640
Compactin0.870 0.870 0.910 0.930 0.990 0.980 0.980
KLA/Compactin0.890 0.960 0.890 0.710 0.660 0.600 0.630
Aldh9a1
KLA  Compactin  Compactin+KLA
 NM_019993 aldehyde dehydrogenase 9, subfamily A1 (Aldh9a1), mRNA [NM_019993] KLA1.020 0.950 0.990 0.900 0.680 0.660 0.630
Compactin1.180 1.040 1.120 1.230 1.070 1.030 0.960
KLA/Compactin1.110 0.940 1.000 0.880 0.670 0.650 0.700
Gulo
KLA  Compactin  Compactin+KLA
 NM_178747 gulonolactone (L-) oxidase (Gulo), mRNA [NM_178747] KLA0.980 0.940 0.940 1.010 1.040 0.970 1.020
Compactin0.990 0.880 0.970 1.010 1.030 1.000 0.950
KLA/Compactin0.970 1.080 0.990 1.000 1.030 0.920 1.020
Gulo
KLA  Compactin  Compactin+KLA
 NM_178747 gulonolactone (L-) oxidase (Gulo), mRNA [NM_178747] KLA1.030 1.010 1.040 0.970 1.000 0.950 0.930
Compactin1.020 1.040 0.980 1.000 0.980 1.010 0.890
KLA/Compactin0.980 0.990 0.980 0.990 1.030 0.990 0.960
Miox
KLA  Compactin  Compactin+KLA
 AF197127 unknown mRNA. [AF197127] KLA1.000 1.120 0.970 1.030 1.060 1.020 1.060
Compactin1.030 0.970 1.030 0.970 1.050 1.080 0.970
KLA/Compactin0.960 1.050 1.020 1.080 1.010 1.000 1.080
Rgn
KLA  Compactin  Compactin+KLA
 NM_009060 regucalcin (Rgn), mRNA [NM_009060] KLA0.970 0.940 1.110 0.990 0.920 0.990 0.970
Compactin0.950 1.010 0.960 1.040 1.040 0.940 1.020
KLA/Compactin0.990 1.060 0.980 0.840 0.990 0.960 1.010
Ugdh
KLA  Compactin  Compactin+KLA
 NM_009466 UDP-glucose dehydrogenase (Ugdh), mRNA [NM_009466] KLA1.180 1.080 1.070 0.980 1.230 1.510 1.460
Compactin1.140 1.160 1.090 1.300 1.110 1.030 1.140
KLA/Compactin1.090 0.960 1.060 1.080 1.470 1.830 1.660
Ugt1a1
KLA  Compactin  Compactin+KLA
 NM_201645 UDP glucuronosyltransferase 1 family, polypeptide A1 (Ugt1a1), mRNA [NM_201645] KLA0.960 1.010 0.960 0.920 1.000 1.110 0.980
Compactin0.950 0.940 0.970 0.900 0.910 0.980 1.050
KLA/Compactin1.040 0.950 0.910 1.050 1.030 0.960 1.000
Ugt1a2
KLA  Compactin  Compactin+KLA
 145699117 UDP glucuronosyltransferase 1 family, polypeptide A2 KLA1.050 0.830 0.910 0.880 0.910 0.890 0.910
Compactin1.060 1.080 0.890 0.940 1.030 0.950 1.040
KLA/Compactin1.040 0.870 0.860 0.800 0.940 0.930 0.870
Ugt1a6a
KLA  Compactin  Compactin+KLA
 145699102 UDP glucuronosyltransferase 1 family, polypeptide A6A KLA0.970 0.790 0.890 0.730 0.870 0.800 0.830
Compactin0.980 0.980 0.980 1.000 1.020 0.890 1.010
KLA/Compactin1.050 0.830 0.850 0.790 0.940 0.810 0.810
Ugt1a6b
KLA  Compactin  Compactin+KLA
 NM_201410 UDP glucuronosyltransferase 1 family, polypeptide A6B (Ugt1a6b), mRNA [NM_201410] KLA0.800 1.040 0.980 1.020 0.990 1.050 1.000
Compactin1.040 0.970 0.980 0.980 1.040 1.020 0.960
KLA/Compactin1.070 1.030 0.970 0.980 0.990 0.990 0.990
Ugt1a6b
KLA  Compactin  Compactin+KLA
 NM_201410 UDP glucuronosyltransferase 1 family, polypeptide A6B (Ugt1a6b), mRNA [NM_201410] KLA0.930 0.900 0.920 0.710 0.470 0.390 0.370
Compactin0.900 0.850 0.900 0.790 1.000 0.840 0.780
KLA/Compactin0.920 0.930 0.900 0.650 0.490 0.400 0.480
Ugt1a9
KLA  Compactin  Compactin+KLA
 NM_201644 UDP glucuronosyltransferase 1 family, polypeptide A9 (Ugt1a9), mRNA [NM_201644] KLA1.000 0.990 0.980 1.030 1.050 1.030 0.980
Compactin1.020 0.960 1.000 0.980 1.090 1.040 0.990
KLA/Compactin1.030 1.100 0.960 0.970 1.040 1.020 0.970
Ugt2a1
KLA  Compactin  Compactin+KLA
 NM_053184 UDP glucuronosyltransferase 2 family, polypeptide A1 (Ugt2a1), mRNA [NM_053184] KLA0.980 1.030 0.990 1.020 1.060 1.020 1.100
Compactin1.020 1.010 0.970 1.000 1.040 1.000 1.020
KLA/Compactin1.020 1.010 0.970 0.940 1.050 1.030 1.030
Ugt2a1
KLA  Compactin  Compactin+KLA
 NM_053184 UDP glucuronosyltransferase 2 family, polypeptide A1 (Ugt2a1), mRNA [NM_053184] KLA0.990 1.010 1.050 1.040 0.990 1.000 1.000
Compactin0.950 0.960 1.070 0.920 0.900 0.970 0.970
KLA/Compactin0.960 0.960 1.000 0.910 0.910 0.970 0.990
Ugt2a1
KLA  Compactin  Compactin+KLA
 NM_053184 UDP glucuronosyltransferase 2 family, polypeptide A1 (Ugt2a1), mRNA [NM_053184] KLA1.000 1.100 1.040 0.950 1.060 1.100 0.980
Compactin0.980 1.040 1.030 1.020 0.930 1.020 1.030
KLA/Compactin1.040 0.980 0.990 1.100 0.980 0.880 0.980
Ugt2a3
KLA  Compactin  Compactin+KLA
 NM_028094 UDP glucuronosyltransferase 2 family, polypeptide A3 (Ugt2a3), mRNA [NM_028094] KLA0.980 1.020 1.020 0.950 1.010 0.960 1.010
Compactin0.990 1.050 0.950 1.030 0.950 0.960 0.980
KLA/Compactin1.020 1.030 0.960 0.980 0.970 0.920 0.970
Ugt2b1
KLA  Compactin  Compactin+KLA
 NM_152811 UDP glucuronosyltransferase 2 family, polypeptide B1 (Ugt2b1), mRNA [NM_152811] KLA0.970 1.020 1.040 1.030 0.990 0.960 0.990
Compactin0.960 0.930 0.990 0.980 1.010 1.010 0.960
KLA/Compactin1.010 1.020 0.960 1.020 1.010 0.960 1.000
Ugt2b34
KLA  Compactin  Compactin+KLA
 NM_153598 UDP glucuronosyltransferase 2 family, polypeptide B34 (Ugt2b34), mRNA [NM_153598] KLA1.410 1.060 1.000 1.070 1.030 0.960 1.110
Compactin1.210 1.000 0.920 1.030 1.050 0.930 1.070
KLA/Compactin1.100 1.030 0.860 1.060 1.040 1.040 1.020
Ugt2b35
KLA  Compactin  Compactin+KLA
 NM_172881 UDP glucuronosyltransferase 2 family, polypeptide B35 (Ugt2b35), mRNA [NM_172881] KLA1.010 1.040 0.960 1.010 0.990 1.030 0.950
Compactin1.020 0.980 0.990 0.980 0.890 0.940 0.970
KLA/Compactin1.000 0.940 1.020 1.030 1.010 0.960 1.000
Ugt2b35
KLA  Compactin  Compactin+KLA
 NM_172881 UDP glucuronosyltransferase 2 family, polypeptide B35 (Ugt2b35), mRNA [NM_172881] KLA1.070 1.020 0.950 1.030 1.000 1.000 1.050
Compactin1.270 0.960 1.030 0.970 0.970 0.960 1.020
KLA/Compactin1.020 1.050 1.050 1.020 1.030 1.030 1.020
Ugt2b36
KLA  Compactin  Compactin+KLA
 NM_001029867 UDP glucuronosyltransferase 2 family, polypeptide B36 (Ugt2b36), mRNA [NM_001029867] KLA1.080 0.990 1.030 0.990 1.020 0.980 1.000
Compactin1.010 0.930 1.040 1.050 1.000 1.000 1.050
KLA/Compactin1.020 0.990 1.080 0.990 1.010 0.960 0.990
Ugt2b37
KLA  Compactin  Compactin+KLA
 NM_053215 UDP glucuronosyltransferase 2 family, polypeptide B37 (Ugt2b37), mRNA [NM_053215] KLA1.050 1.010 0.930 0.980 0.980 0.900 0.860
Compactin1.020 1.010 1.050 0.960 1.110 1.070 0.930
KLA/Compactin0.990 0.940 0.970 1.050 0.890 0.890 0.870
Ugt2b37
KLA  Compactin  Compactin+KLA
 NM_053215 UDP glucuronosyltransferase 2 family, polypeptide B37 (Ugt2b37), mRNA [NM_053215] KLA1.100 0.960 1.100 0.930 0.900 0.970 0.900
Compactin1.040 1.020 0.970 0.960 1.010 1.010 0.960
KLA/Compactin1.050 1.030 1.090 0.970 1.020 0.920 0.860
Ugt2b38
KLA  Compactin  Compactin+KLA
 NM_133894 UDP glucuronosyltransferase 2 family, polypeptide B38 (Ugt2b38), mRNA [NM_133894] KLA1.040 1.040 0.970 0.990 0.970 0.930 0.920
Compactin1.060 1.070 1.080 1.040 1.040 1.110 0.980
KLA/Compactin0.900 1.040 1.030 1.030 0.980 1.010 1.010
Ugt2b5
KLA  Compactin  Compactin+KLA
 NM_009467 UDP glucuronosyltransferase 2 family, polypeptide B5 (Ugt2b5), mRNA [NM_009467] KLA0.930 1.070 1.010 0.930 1.010 0.980 1.070
Compactin1.020 0.970 0.950 1.070 1.020 1.000 1.010
KLA/Compactin0.980 0.970 0.990 1.030 1.020 0.990 0.980