Lipidomics Studies on Bone Marrow-derived Macrophages Treated with ATP / Kdo2-Lipid A
Glycerophospholipids
Legend:
: View data/graphs for replicates
Kdo+ATP = (Kdo2-Lipid A + ATP)/Control
Kdo = Kdo2-Lipid A/Control; ATP = ATP/Control
RepressionInduction
Measurements were in pmol/ug DNA [Averaged DNA values]
Legend: :Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
-
PG(34:1)
1.23
1.14
0.861
0.868
0.765
0.567
0.978
1.32
1.29
1.51
1.03
0.862
0.815
1.09
0.906
1.14
1.16
1.05
1.07
1.59
1.14
Legend: :Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
-
PG(34:2)
0.855
0.774
0.786
1.06
0.693
0.634
0.685
0.911
1
1.17
1.03
1.09
0.914
1.09
1.22
2.84
0.864
1.23
0.323
0.404
0.343
Legend: :Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
-
PG(34:3)
0.693
0.576
0.625
1.11
1.03
0.744
0.647
0.804
0.503
0.744
0.691
0.454
0.971
1.06
0.874
1.03
0.881
0.791
0.95
0.592
0.636
Legend: :Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
-
PG(36:0)
0.963
0.279
0.453
1.31
0.444
0.205
0.635
0.645
0.446
0.517
0.267
0.041
0.839
1.31
0.415
0.818
1.38
0.499
1.69
4.87
3.5
Legend: :Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
-
PG(36:1)
0.937
1.1
0.714
0.904
0.624
0.622
0.616
0.861
0.835
0.711
0.567
0.517
0.905
1.08
1.01
0.856
0.977
0.636
0.908
1.71
1.32
Legend: :Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
-
PG(36:2)
0.789
0.863
0.717
0.991
0.721
0.783
0.764
0.972
1.07
0.998
0.873
0.811
0.995
0.974
0.984
1.31
0.861
0.947
0.713
0.915
0.823
Legend: :Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
-
PG(36:3)
0.789
0.841
0.778
1.01
0.78
0.761
0.826
0.949
1.01
1.41
1.29
1.09
1.18
1.11
1.08
1.72
1.08
1.32
1.17
0.848
0.947
Legend: :Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
-
PG(36:4)
0.767
0.72
0.427
0.849
0.371
0.314
1.38
1.05
1.47
0.246
0.219
0.183
2.2
1.13
1.22
1.79
1.21
0.427
1.28
1.65
0.366
Legend: :Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
-
PG(38:2)
0.768
0.77
0.699
0.969
0.586
0.638
0.801
0.865
0.761
1.86
1.38
1.52
0.923
1.04
0.971
0.678
0.771
0.594
0.716
1.01
0.947
Legend: :Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
-
PG(38:3)
0.858
0.908
0.721
0.828
0.579
0.586
0.882
0.988
0.882
1.9
1.6
1.31
1.05
1.06
1.12
1.11
0.773
0.704
0.943
0.78
0.819
Legend: :Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
-
PG(38:4)
0.91
0.957
0.761
1.13
0.719
0.722
0.878
0.999
0.929
1.99
1.59
1.56
1.3
1.08
1.31
1.43
0.835
0.861
1.3
0.764
0.838
Legend: :Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
-
PG(38:5)
0.97
1.01
0.699
1.06
0.805
0.747
0.998
1.06
0.961
1.3
1.1
0.751
1.23
1.26
1.4
1.53
0.909
1.11
1.34
0.944
0.703
Legend: :Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
-
PG(38:6)
0.896
0.904
0.622
1.25
0.622
0.672
0.819
0.81
0.681
1.09
1.13
0.723
1.37
1
1.12
0.884
0.823
0.624
1.04
0.747
0.588
Legend: :Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
-
PG(40:4)
0.754
0.849
0.683
1.26
0.523
0.752
0.711
0.62
0.504
1.02
0.802
0.621
0.97
0.955
1.27
0.883
0.758
0.529
0.788
0.669
0.675
Legend: :Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
-
PG(40:5)
0.733
0.632
0.569
1.23
0.615
0.594
1.01
0.828
0.729
1.28
1.02
0.85
1.11
1.03
1.33
0.569
0.518
0.5
0.977
0.741
0.712
Legend: :Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
-
PG(40:6)
0.844
0.919
0.762
1.48
0.642
0.72
0.854
0.864
0.787
1.21
1.02
0.872
1.3
1.16
1.37
1.34
0.836
0.673
0.944
0.754
0.719
Legend: :Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
-
PG(40:7)
0.777
0.819
0.673
1.14
0.745
0.719
0.755
0.862
0.815
0.928
0.805
0.826
1.24
1.09
1.3
1.42
0.868
0.798
1.05
0.881
0.734
Legend: :Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
-
PG(40:8)
0.974
0.922
0.602
1.36
0.658
0.718
0.627
0.776
0.68
0.689
0.764
0.526
1.22
1.13
0.862
0.908
0.895
0.831
1.69
0.707
0.709
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