Lipidomics Studies on Bone Marrow-derived Macrophages Treated with ATP / Kdo2-Lipid A
Glycerophospholipids
|
Induction
| Details | Graph | LM_ID | Name | Kdo+ATP Kdo ATP 15 min |
Kdo+ATP Kdo ATP 30 min |
Kdo+ATP Kdo ATP 1 hr |
Kdo+ATP Kdo ATP 2 hrs |
Kdo+ATP Kdo ATP 4 hrs |
Kdo+ATP Kdo ATP 8 hrs |
Kdo+ATP Kdo ATP 20 hrs |
|---|---|---|---|---|---|---|---|---|---|---|
 |
Legend:
 :Ctrl
 :Kdo2-lipid A
 :ATP
 :ATP+Kdo2-lipid A
| - | PC(28:0) | 1.02
0.614
2.5
| 1.46
0.45
0.574
| 0.561
1.18
0.908
| 3.85
1.03
7.21
| 1.77
0.928
0.455
| 1.79
2.11
2.55
| 1.33
1.76
1.39
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
| - | PC(32:0) | 2.16
1.32
1.07
| 1.06
0.701
0.583
| 0.616
1.21
0.895
| 2.2
1.86
1.5
| 1.35
1.09
0.89
| 1.72
1.46
1.39
| 1.09
1.7
1.36
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
| - | PC(32:1) | 1.47
1.56
1.52
| 1.45
0.77
0.672
| 0.533
0.646
0.595
| 1.06
1.08
0.876
| 1.77
1.43
1.3
| 0.853
0.784
0.694
| 0.583
0.77
0.791
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
| - | PC(32:2) | 1.11
1.37
1.38
| 0.947
0.862
0.708
| 0.849
0.724
0.745
| 1.15
1.52
2.37
| 2.24
1.07
0.739
| 0.937
0.768
1.13
| 0.717
0.7
1.03
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
| - | PC(34:1) | 1.38
1.17
1.19
| 0.964
0.702
0.752
| 0.754
1.04
0.733
| 2.18
1.61
1.09
| 1.39
0.799
1.01
| 1.57
1.08
1.33
| 0.667
0.858
0.834
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
| - | PC(34:2) | 1.59
1.14
1.2
| 1.06
0.701
0.776
| 0.713
0.958
0.743
| 2.09
1.48
1.45
| 1.32
0.958
0.901
| 1.45
0.861
1.39
| 0.622
0.805
0.829
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
| - | PC(34:3) | 0.673
0.957
0.469
| 0.799
0.74
0.763
| 0.523
0.403
0.399
| 3.03
0.833
0.66
| 1.86
1.1
1.21
| 0.553
0.413
0.422
| 5.47
2.71
1.18
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
| - | PC(36:0) | 9.43
3.13
4.21
| 14.8
1.11
1.74
| 0.336
1.96
0.332
| 4.63
2.3
7.13
| 2.34
1.49
1.89
| 0.424
0.916
0.525
| 0.509
0.417
0.527
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
| - | PC(36:1) | 1.02
1.2
0.884
| 0.979
0.814
0.677
| 0.517
0.826
0.625
| 1.76
1.89
1.37
| 1.49
1.15
0.97
| 1.37
1.04
1.16
| 0.676
0.985
0.838
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
| - | PC(36:2) | 1.22
1.11
0.876
| 0.998
0.681
0.757
| 0.714
0.996
0.645
| 1.73
1.63
1.13
| 1.26
1
0.982
| 1.38
0.871
0.947
| 0.484
0.673
0.585
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
| - | PC(36:2e)/PC(36:1p) | 1.05
1.49
1.62
| 1.06
0.732
0.6
| 0.826
0.826
0.914
| 2.24
1.47
1.23
| 0.875
0.924
0.733
| 1.17
0.807
1.12
| 0.544
0.536
0.573
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
| - | PC(36:3) | 1.02
1.2
0.979
| 1.08
0.717
0.843
| 0.667
0.743
0.671
| 1.22
1.08
1.13
| 2.58
1.09
1.52
| 1.33
0.912
0.991
| 0.651
0.55
0.679
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
| - | PC(36:3e)/PC(36:2p) | 2.48
1.84
2.36
| 1.08
0.545
0.784
| 0.727
0.662
0.632
| 3.89
1.39
1.82
| 2.91
1.26
0.782
| 0.949
0.692
0.857
| 0.59
0.455
0.544
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
| - | PC(36:4) | 1.22
1.25
1.21
| 1.47
0.835
1.03
| 0.794
0.752
0.738
| 2.25
1.44
1.14
| 2.03
0.927
1.11
| 1.78
1.02
1.13
| 0.446
0.446
0.507
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
| - | PC(36:4e)/PC(36:3p) | 0.916
1.74
1.75
| 0.902
0.459
0.447
| 0.849
0.704
0.669
| 3.5
1.38
2.77
| 1.93
0.768
0.933
| 1.94
0.671
1.08
| 0.566
0.258
0.392
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
| - | PC(36:5e)/PC(36:4p) | 1.9
1.12
1.07
| 0.653
1.06
0.683
| 2.89
0.599
0.924
| 2.72
1.4
1.47
| 2.56
2.04
1.26
| 1.81
0.961
1.36
| 1.4
1.83
0.938
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
| - | PC(38:3) | 2.27
1.28
1.88
| 1.49
0.673
0.356
| 0.841
1.58
1.32
| 1.62
1.67
2.41
| 2.39
1.75
1.1
| 0.541
0.538
0.656
| 0.516
0.506
0.618
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
| - | PC(38:4) | 0.948
1.32
0.787
| 0.949
0.651
0.577
| 0.663
0.694
0.597
| 1.2
1.4
1.19
| 2.65
1.43
1.2
| 1.55
0.941
0.985
| 0.512
0.422
0.581
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
| - | PC(38:5) | 0.964
1.22
0.891
| 1.37
0.81
0.761
| 0.714
0.891
0.709
| 1.59
1.91
1.21
| 1.92
1.33
1.02
| 1.13
0.685
0.819
| 0.584
0.496
0.628
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
| - | PC(38:5e)/PC(38:4p) | 1.74
1.45
2.26
| 1.35
0.864
0.419
| 0.935
0.696
1.19
| 1.37
1.3
1.28
| 2.22
1.47
1.27
| 1.63
1.16
1.24
| 0.586
0.782
0.842
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
| - | PC(38:6) | 1.44
1.32
1.3
| 1.41
0.876
0.761
| 0.958
1.09
0.911
| 1.92
1.64
1.55
| 1.7
1.06
1.18
| 1.62
0.979
1.42
| 0.637
0.684
0.812
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
| - | PC(38:6e)/PC(38:5p) | 1.39
2.96
1.62
| 2.12
1.05
1.07
| 1.28
0.52
0.814
| 1.46
1.04
0.857
| 1.95
1.17
1.3
| 0.946
0.783
0.826
| 0.504
0.727
0.875
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
| - | PC(40:4) | 0.75
1.47
2.6
| 1.93
0.683
0.961
| 1.68
0.802
0.51
| 3.28
1.39
4.58
| 2.62
2.83
1.75
| 1.05
0.719
1.09
| 0.592
0.559
0.572
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
| - | PC(40:5) | 0.955
1.06
0.922
| 1.05
0.689
0.668
| 1.17
0.93
0.607
| 3
1.86
2.5
| 2.12
2.43
1.09
| 1.58
0.866
0.937
| 0.717
0.689
0.612
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
| - | PC(40:6) | 1.8
1.45
1.69
| 1.15
0.974
0.546
| 0.754
0.764
0.496
| 1.74
1.31
1.68
| 1.67
0.786
0.881
| 0.997
0.766
0.729
| 0.535
0.628
0.849
|